Method for increasing the rate and consistency of bioavailability of supplemental dietary ingredients

Abstract

The present invention relates to a method for increasing the rate of bioavailability of orally administered supplemental dietary ingredients through the process of fine-milling to increase the rate of dissolution of the ingredients. The ingredients to be fine-milled are ingredients suitable for use in supplemental dietary compositions.

1 . A method for increasing the rate of bioavailability of a supplemental dietary ingredient in a mammal, the method comprising the step of: 
 fine-milling said ingredient such that, upon administration of said fine-milled ingredient to said mammal, the immediacy of absorption of said supplemental dietary ingredient in said mammal is improved as compared to an immediacy of absorption of said ingredient when said ingredient is in a regular form.    
   
   
       2 . The method of  claim 1 , whereby the improved immediacy of absorption is the result of an increased rate of dissolution of said supplemental dietary ingredient in said mammal, thereby increasing the rate of bioavailability of said supplemental dietary ingredient.  
   
   
       3 . The method of  claim 1 , wherein said fine-milled supplemental dietary ingredient is suitable to be orally administered.  
   
   
       4 . The method of  claim 1 , further comprising the step of: 
 providing said fine-milled supplemental dietary ingredient in a composition, the composition including said ingredient in a regular form.    
   
   
       5 . The method of  claim 4 , wherein the ratio of regular form to fine-milled form of said supplemental dietary ingredient is from about 5:1 to about 10,000:1.  
   
   
       6 . The method of  claim 1 , wherein said fine-milled particles have an average size range of between from about 2 to about 50 microns.  
   
   
       7 . A method for improving the consistency of the rate of digestive absorption of a supplemental dietary ingredient in a mammal, the method comprising the step of: 
 fine-milling said ingredient so as to improve a uniformity of particles sizes of said ingredient, such that, upon administration of said fine-milled ingredient to said mammal, the consistency of the rate of digestive absorption is improved as compared to a rate of digestive absorption of said ingredient in regular form due to said improved uniformity of the particle size.    
   
   
       8 . The method of  claim 7 , wherein said fine-milled particles have an average size range of between about 2 to about 50 microns.  
   
   
       9 . A method for manufacturing a supplemental dietary composition suitable for ingestion by a mammal, the method comprising the step of: 
 providing in the supplemental dietary composition an ingredient, the ingredient being fine-milled such that, upon administration of said fine-milled ingredient to said mammal, a rate of bioavailability of said ingredient is improved as compared to a rate of bioavailability of said ingredient when said ingredient is in a regular form.    
   
   
       10 . The method of  claim 9 , wherein said supplemental dietary composition having said ingredient is suitable to be ingested orally.  
   
   
       11 . The method of  claim 9 , further comprising the step of providing in the supplemental dietary composition said ingredient in a regular form.  
   
   
       12 . The method of  claim 11 , wherein the ratio of regular form to fine-milled form of said ingredient is from about 5:1 to about 10,000:1.  
   
   
       13 . The method of  claim 9 , wherein said fine-milled ingredient includes particles having an average size range between about 2 and about 50 microns.  
   
   
       14 . A method for manufacturing a supplemental dietary composition suitable for ingestion by a mammal, the method comprising the step of: 
 providing in the supplemental dietary composition an ingredient, the ingredient being fine-milled such that, upon administration of said fine-milled ingredient to said mammal, an immediacy of absorption of said ingredient is improved as compared to an immediacy of absorption of said ingredient when said ingredient is in a regular form.    
   
   
       15 . The method of  claim 14 , wherein said supplemental dietary composition having said ingredient is suitable to be ingested orally.  
   
   
       16 . The method of  claim 14 , further comprising the step of providing in the supplemental dietary composition said ingredient in a regular form.  
   
   
       17 . The method of  claim 16 , wherein the ratio of regular form to fine-milled form of said ingredient is from about 5:1 to about 10,000:1.  
   
   
       18 . The method of  claim 14 , wherein said fine-milled ingredient includes particles having an average size range between about 2 and about 50 microns.  
   
   
       19 . A method for manufacturing a supplemental dietary composition suitable for ingestion by a mammal, the method comprising the step of: 
 providing in the supplemental dietary composition an ingredient, the ingredient being fine-milled such that, upon administration of said fine-milled ingredient to said mammal, a rate of dissolution of said ingredient is improved as compared to a rate of dissolution of said ingredient when said ingredient is in a regular form.    
   
   
       20 . The method of  claim 19 , wherein said supplemental dietary composition having said ingredient is suitable to be ingested orally.  
   
   
       21 . The method of  claim 19 , further comprising the step of providing in the supplemental dietary composition said ingredient in a regular form.  
   
   
       22 . The method of  claim 21 , wherein the ratio of regular form to fine-milled form of said ingredient is from about 5:1 to about 10,000:1.  
   
   
       23 . The method of  claim 19 , wherein said fine-milled ingredient includes particles having an average size range between about 2 and about 50 microns.  
   
   
       24 . A method for manufacturing a supplemental dietary composition suitable for ingestion by a mammal, the method comprising the step of: 
 providing in the supplemental dietary composition an ingredient, the ingredient being fine-milled such that, upon administration of said fine-milled ingredient to said mammal, a consistency of the rate of digestive absorption of the ingredient is improved as compared to a consistency of the rate of digestive absorption of the ingredient when said ingredient is in a regular form.    
   
   
       25 . The method of  claim 24 , wherein said supplemental dietary composition having said ingredient is suitable to be ingested orally.  
   
   
       26 . The method of  claim 24 , further comprising the step of providing in the supplemental dietary composition said ingredient in a regular form.  
   
   
       27 . The method of  claim 26 , wherein the ratio of regular form to fine-milled form of said ingredient is from about 5:1 to about 10,000:1.  
   
   
       28 . The method of  claim 24 , wherein said fine-milled ingredient includes particles having an average size range between about 2 and about 50 microns.  
   
   
       29 . A method for manufacturing a supplemental dietary composition suitable for ingestion by a mammal, the method comprising the step of: 
 providing in the supplemental dietary composition an ingredient, the ingredient being fine-milled such that a uniformity of particles sizes of said ingredient is improved as compared to a uniformity of particles sizes of said ingredient when said ingredient is in a regular form.    
   
   
       30 . The method of  claim 29 , wherein said supplemental dietary composition having said ingredient is suitable to be ingested orally.  
   
   
       31 . The method of  claim 29 , further comprising the step of providing in the supplemental dietary composition said ingredient in a regular form.  
   
   
       32 . The method of  claim 31 , wherein the ratio of regular form to fine-milled form of said ingredient is from about 5:1 to about 10,000:1.  
   
   
       33 . The method of  claim 29 , wherein said fine-milled ingredient includes particles having an average size range between about 2 and about 50 microns.  
   
   
       34 . A supplemental dietary composition suitable for ingestion by a mammal, comprising: 
 a fine-milled ingredient which, upon administration of said fine-milled ingredient to said mammal, has a rate of bioavailability that is improved as compared to a rate of bioavailability of said ingredient when said ingredient is in a regular form.    
   
   
       35 . The method of  claim 34 , wherein said supplemental dietary composition having said ingredient is suitable to be ingested orally.  
   
   
       36 . The method of  claim 34 , further comprising the step of providing in the supplemental dietary composition said ingredient in a regular form.  
   
   
       37 . The method of  claim 36 , wherein the ratio of regular form to fine-milled form of said ingredient is from about 5:1 to about 10,000:1.  
   
   
       38 . The method of  claim 34 , wherein said fine-milled ingredient includes particles having an average size range between about 2 and about 50 microns.