Oral compositions comprising siloxane polymers

Abstract

Oral compositions are provided that comprise an active ingredient comprising a siloxane polymer having at least one hydrophilic region. The oral care composition comprises a siloxane polymer having a phosphorus-containing moiety. A source of fluoride ions and/or other oral care actives can be included in the oral care composition. Methods of making and using the oral compositions are also provided.

1 . An oral care composition comprising a siloxane polymer having a phosphorus-containing moiety. 
   
   
       2 . A composition according to  claim 1 , wherein at least one of the moieties comprising phosphorus is selected from the group consisting of: phosphate, phosphonate, phospholipids, a phosphate-containing group, and combinations thereof. 
   
   
       3 . A composition according to  claim 1 , wherein the siloxane polymer comprises a compound having the formula: 
     
       
         
         
             
             
         
       
     
     wherein R 1  is selected from the group consisting of: alkyl, aryl, amide, ester, pyrrolidone, vinyl, acrylate, siloxane, urethane, carbonate, vinyl alcohol, alkylene oxide, and combinations thereof; and R 2  comprises a moiety selected from the group consisting of: phosphate, phosphonate, phospholipids, a phosphate-containing group, and combinations thereof, “x” is 0 to 100 and “y” is 1 to 100. 
   
   
       4 . A composition according to  claim 3 , wherein R 1  has the formula: —(CH 2 ) v -(Q) z , where Q is at least one group selected from: C 2 H 2 O, C 3 H 6 O; CH 2 CH(OH); 
     CONH,CO 2 , NH, CONH, 
     
       
         
         
             
             
         
       
     
     wherein “v” and “z” are 1 to 16. 
   
   
       5 . An oral care composition according to  claim 1  comprising about 0.001 to about 3% by weight of the siloxane polymer. 
   
   
       6 . A composition according to  claim 1 , wherein the composition comprises an ingredient selected from the group consisting of: surface active agents, viscosity modifiers, thickeners, humectants, diluents, fillers, pH modifying agents, plasticizers, fillers, waxes, texture modifiers, flavoring agents, sweetening agents, coloring agents, preservatives, solvents, and mixtures thereof. 
   
   
       7 . A composition according to  claim 1 , further comprising an active ingredient selected from the group consisting of an antimicrobial agent, an antitartar agent, an anti-plaque, an anticaries agent, a biofilm disruption agent, an antioxidant, an anti-inflammatory agent, a tooth whitening agent, an anti-adhesion agent, a desensitizing agent, a malodor control agent, a flavoring agent, a coloring agent, an anti-aging agent, a salivary stimulant, a periodontal active, a conditioning agent, a natural extract, an essential oil, a nutrient, an enzyme, a protein, an amino acid, a vitamin, an analgesic, and mixtures thereof. 
   
   
       8 . An oral care composition comprising a siloxane polymer having a phosphorus-containing moiety, wherein the siloxane polymer is an anti-attachment agent that substantially inhibits bacteria from forming a biofilm on a tooth surface. 
   
   
       9 . An oral care composition according to  claim 8 , wherein the moiety containing phosphorus is selected from the group consisting of: phosphate, phosphonate, phospholipids, a phosphate-containing group, and combinations thereof. 
   
   
       10 . An oral care composition according to  claim 9 , wherein the siloxane polymer comprises an alkyl phosphate siloxane. 
   
   
       11 . An oral care composition according to  claim 9 , wherein the siloxane polymer comprises a polydimethylsiloxane phosphate. 
   
   
       12 . An oral care composition according to  claim 8 , wherein the siloxane polymer comprises a compound having the formula: 
     
       
         
         
             
             
         
       
     
     wherein R 1  is selected from the group consisting of: alkyl, aryl, amide, ester, pyrrolidone, vinyl, acrylate, siloxane, urethane, carbonate, vinyl alcohol, alkylene oxide, and combinations thereof; and R 2  comprises a moiety selected from the group consisting of: phosphate, phosphonate, phospholipids, a phosphate-containing group, and combinations thereof, “x” is 0 to 100 and “y” is 1 to 100. 
   
   
       13 . An oral care composition according to  claim 12 , wherein R 1  has the formula: 
     —(CH 2 ) v -(Q) z , where Q is at least one group selected from: C 2 H 2 O, C 3 H 6 O; CH 2 CH(OH); 
     
       
         
         
             
             
         
       
     
     CONH,CO 2 , NH, CONH, wherein “v” and “z” are 1 to 16. 
   
   
       14 . An oral care composition according to  claim 8 , wherein the siloxane polymer comprises a compound having the formula: 
     
       
         
         
             
             
         
       
       wherein R 2  is —PO 3 H 2  or —(CH 3 CH 2 H 3 O) n PO 3 H 2 , “x” is 0 to 100, “y” is 1 to 100, and “m” is 0 to 15. 
     
   
   
       15 . An oral care composition according to  claim 8 , wherein the siloxane polymer comprises a compound having the formula: 
     
       
         
         
             
             
         
       
     
     wherein R 3  is an alkyl group, “x” is 0 to 100, and “y” is 1 to 100. 
   
   
       16 . An oral care composition according to  claim 15 , wherein R 3  is a C 1-8  alkyl group. 
   
   
       17 . An oral care composition according to  claim 8  comprising about 0.001 to about 3% by weight of the siloxane polymer. 
   
   
       18 . An oral care composition according to  claim 8 , further comprising an active ingredient selected from the group consisting of an antimicrobial agent, an antitartar agent, an anti-plaque, an anticaries agent, a biofilm disruption agent, an antioxidant, an anti-inflammatory agent, a tooth whitening agent, an anti-adhesion agent, a desensitizing agent, a malodor control agent, a flavoring agent, a coloring agent, an anti-aging agent, a salivary stimulant, a periodontal active, a conditioning agent, a natural extract, an essential oil, a nutrient, an enzyme, a protein, an amino acid, a vitamin, an analgesic, and mixtures thereof. 
   
   
       19 . An oral care composition according to  claim 8 , further comprising a carrier ingredient selected from the group consisting of surface active agents, viscosity modifiers, thickeners, humectants, diluents, pH modifying agents, emollients, moisturizers, mouth feel agents, sweetening agents, flavoring agents, solvent, water, colorants, preservatives, and mixtures thereof. 
   
   
       20 . An oral composition comprising an anti-plaque and/or antitartar active ingredient comprising a siloxane polymer having at least one hydrophilic region, wherein the siloxane polymer is an anti-attachment agent that substantially inhibits bacteria from forming a biofilm on a tooth surface, and wherein the composition is substantially free of lipophilic active ingredients. 
   
   
       21 . An oral composition according to  claim 20 , wherein the hydrophilic region comprises a moiety selected from the group consisting of: alkylene oxides, phosphates, phosphonates, phospholipids, amines, and combinations thereof. 
   
   
       22 . An oral composition according to  claim 20 , wherein the siloxane polymer comprises a compound having the formula: 
     
       
         
         
             
             
         
       
     
     wherein R 4  is selected from H or —PO 3 H 2 , “x” is 0 to 100, “y” is 1 to 100, “m” is 0 to 15, and “n” is 0 to 15. 
   
   
       23 . An oral composition according to  claim 20 , wherein the siloxane polymer comprises a compound having the formula: 
     
       
         
         
             
             
         
       
     
     wherein “x” is 0 to 100, “y” is 1 to 100, and “m” is 0 to 15. 
   
   
       24 . An oral composition according to  claim 20 , wherein the siloxane polymer comprises a compound having the formula: 
     
       
         
         
             
             
         
       
     
     wherein R 1  is selected from the group consisting of: alkyl, aryl, amide, ester, pyrrolidone, vinyl, acrylate, siloxane, urethane, carbonate, vinyl alcohol, alkylene oxide, and combinations thereof; and R 2  comprises a moiety selected from the group consisting of: phosphate, phosphonate, phospholipids, a phosphate-containing group, and combinations thereof, “x” is 0 to 100 and “y” is 1 to 100. 
   
   
       25 . An oral composition according to  claim 20 , wherein the siloxane polymer comprises a compound having the formula: 
     
       
         
         
             
             
         
       
     
     wherein R 2  is —PO 3 H 2  or —(CH 3 CH 2 H 3 O) N PO 3 H 2 , “x” is 0 to 100, “y” is 1 to 100, and “m” is 0 to 15. 
   
   
       26 . An oral composition according to  claim 20 , wherein the siloxane polymer comprises a compound having the formula: 
     
       
         
         
             
             
         
       
       wherein R 3  is a C 18  alkyl group, “x” is 0 to 100, and “y” is 1 to 100. 
     
   
   
       27 . An oral composition according to  claim 20  comprising about 0.001 to about 3% by weight of the siloxane polymer. 
   
   
       28 . An oral composition according to  claim 20 , further comprising a non-lipophilic active ingredient selected from the group consisting of an anticaries agent, a biofilm disruption agent, an antioxidant, an anti-inflammatory agent, a tooth whitening agent, an anti-adhesion agent, a desensitizing agent, a malodor control agent, a flavoring agent, a coloring agent, an anti-aging agent, a salivary stimulant, a periodontal active, a conditioning agent, a natural extract, an essential oil, a nutrient, an enzyme, a protein, an amino acid, a vitamin, an analgesic, and mixtures thereof.