US2007276133A1PendingUtilityA1

5-hydroxytryptophol (5-HTOL) derivatives, antibodies, immunoassays and detection of recent alcohol consumption

Assignee: AXIS BIOCHEMICALS ASAPriority: Dec 5, 1996Filed: Jan 3, 2007Published: Nov 29, 2007

Est. expiryDec 5, 2016(expired)· nominal 20-yr term from priority

Inventors:Ragnhild Brandt Olof Beck Anders Helander Rose-Marie Jonsson Eric Unger Stefan Borg Eva Akerblom

Y10T436/17C07H 17/02Y10T436/145555Y10T436/14Y10T436/203332Y10T436/25C07K 16/44Y10T436/173845

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References

Claims

Abstract

Antibody specific for a 5-HTOL compound. A glucuronide with 5-hydroxytryptophol (5-HTOL) characterized in that it comprises the structure of the β-glucuronide between the 5-hydroxy group of 5-HTOL and D-glucopyranosiduronic acid. An immunoassay and a diagnostic method utilizing the immunoassay wherein a 5-hydroxytryptophol (5-HTOL) compound is determined by the use of an antibody specific for a 5-HTOL compound is used.

Claims

exact text as granted — not AI-modified

1 - 11 . (canceled)  
   
   
       12 . A 3-(2-hydroxyethyl)indole-5-O-β-D-glucopyranosiduronic acid derivative comprising a covalently attached analytically detectable label.  
   
   
       13 . A derivative as claimed in  claim 12  wherein said label is attached at the carboxy group.

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