Therapeutic Agent for Polycystic Ovary Syndrome (Pcos)

Abstract

The present invention provides a therapeutic agent for treating polycystic ovary syndrome (PCOS), which exhibits few, if any, side effects, is effective at inducing ovulation, and is safely available for not only females who desire to bear children, but also for unmarried or young females. A therapeutic agent for polycystic ovary syndrome (PCOS) in which an extract of mushrooms is contained as the active ingredient thereof is used.

1 . A therapeutic agent for treating polycystic ovary syndrome (PCOS) comprising an extract of mushrooms as an active ingredient thereof.  
     
     
         2 . A therapeutic agent for treating polycystic ovary syndrome (PCOS) according to  claim 1 , wherein the mushrooms are at least one selected from the group consisting of  Grifola frondosa, Polyporus umbellatus, Meripilus giganteus, Grifola albicans, Lentinus edodes, Agaricus blazei Murill, Agaricus bispirus, Canoderma applanatum, Fomilopsis pinicola, Coriolus versicolor, Ganoderma lucidum, Pleurotus ostreatus, Pleurotus eryngii, Hericium erinaceus, Cordyceps sinensis, Cordyceps sobolifera, Auricularia auricula, Tremella fuciformis,  and  Phellinus linteus.    
     
     
         3 . A therapeutic agent for treating polycystic ovary syndrome (PCOS) according to  claim 1 , wherein the mushrooms are at least one selected from the group consisting of  Grifola frondosa, Lentinus edodes, Agaricus blazei Murill, Ganoderma lucidum,  and  Pleurotus ostreatus.    
     
     
         4 . A therapeutic agent for treating polycystic ovary syndrome (PCOS) according to  claim 1 , wherein the mushroom is  Grifola frondosa.    
     
     
         5 . A therapeutic agent for treating polycystic ovary syndrome (PCOS) according to any one of  claims 1  to  4 , wherein the extract of the mushrooms is prepared by a process comprising: 
 (1) a step of treating a raw material of the mushrooms with ethanol having a concentration of 90% or more, and thereby removing ethanol-soluble components;    (2) a step of conducting a hot-water extraction thereafter, adding the ethanol to the obtained hot-waterextracted liquid until a final ethanol concentration thereof becomes 50 to 75% by value, removing produced insoluble components, and thereby obtaining a supernatant; and    (3) a step of collecting a fraction having a molecular weight of 14,000 Dalton or more from the supernatant.