Implantable prosthetic valve

Abstract

A valve prosthesis device is disclosed suitable for implantation in body ducts. The device comprises a support stent, comprised of a deployable construction adapted to be initially crimped in a narrow configuration suitable for catheterization through the body duct to a target location and adapted to be deployed by exerting substantially radial forces from within by means of a deployment device to a deployed state in the target location, and a valve assembly comprising a flexible conduit having an inlet end and an outlet, made of pliant material attached to the support beams providing collapsible slack portions of the conduit at the outlet. The support stent is provided with a plurality of longitudinally rigid support beams of fixed length. When flow is allowed to pass through the valve prosthesis device from the inlet to the outlet, the valve assembly is kept in an open position, whereas a reverse flow is prevented as the collapsible slack portions of the valve assembly collapse inwardly providing blockage to the reverse flow.

1 - 49 . (canceled)  
     
     
         50 . A prosthetic valve assembly for use in replacing a deficient native valve, the valve assembly comprising: 
 a valve having a plurality of leaflets, a base, and a plurality of commissure points;    a valve support comprising a generally cylindrical band comprising a plurality of expandable cells, the valve support configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is positioned in situ, said generally cylindrical band of the valve support supporting the base and the commissure points of the valve.    
     
     
         51 . The valve assembly of  claim 50 , wherein one or more of the commissure points of the valve are positioned and secured at or adjacent one of the expandable cells.  
     
     
         52 . The valve assembly of  claim 50 , further comprising: 
 an anchor for engaging the lumen wall when expanded in place for preventing substantial migration of the valve assembly after deployment;    wherein the anchor is itself configured to be expandable, and wherein at least part of the anchor is positioned away from the generally cylindrical band of the valve support.    
     
     
         53 . (canceled)  
     
     
         54 . The valve assembly of  claim 52 , wherein the anchor has an expanded diameter that is different from the expanded diameter of the valve support.  
     
     
         55 . (canceled)  
     
     
         56 . The valve assembly of  claim 50 , further comprising: 
 an anchor for engaging the lumen wall when expanded in place for preventing substantial migration of the valve assembly after deployment:    wherein the anchor comprises one or more hooks extending radially outward from the valve support.    
     
     
         57 . The valve assembly of  claim 56 , wherein the valve support comprises nickel titanium.  
     
     
         58 . A method of replacing a deficient native valve comprising the steps of: 
 providing a prosthetic valve assembly, the assembly comprising a valve, a valve support comprising a plurality of expandable cells and having the base and the commissures of the valve positioned and secured at or adjacent the expandable cells;    collapsing the valve support and anchor to fit on a distal portion of a catheter;    advancing the catheter to the deficient native valve to a position within adjacent the leaflets and within the annulus of the deficient native valve;    deploying the valve assembly within the deficient native valve, whereby the valve support expands against the leaflets of the deficieint native valve; and    withdrawing the catheter, leaving the valve assembly to function in place of the deficient native valve.    
     
     
         59 . The method of  claim 58 , further comprising the step of positioning the valve support and anchor within a generally tubular sheath extending around the distal portion of the catheter.  
     
     
         60 . The method of  claim 58 , wherein the anchor is self-expanding.  
     
     
         61 . The method of  claim 58 , wherein the valve support is self-expanding.  
     
     
         62 . The method of  claim 58 , wherein the valve support is balloon-expandable.  
     
     
         63 . The method of  claim 58 , further comprising the step of securing a portion of the valve support to the catheter.  
     
     
         64 . The method of  claim 58 , wherein deploying the valve assembly comprises the step of crushing the native valve leaflets against the native valve annulus.  
     
     
         65 . (canceled)  
     
     
         66 . The method of  claim 67 , wherein the anchor is spaced from the valve support.  
     
     
         67 . The method of  claim 58 , wherein the prosthetic valve assembly further comprises an anchor for engaging a lumen wall for preventing substantial migration of the valve assembly when positioned in place.  
     
     
         68 . A prosthetic valve assembly for use in replacing a deficient native valve, the valve assembly comprising: 
 a valve having a plurality of leaflets and commissure points;    a valve support comprising a plurality of expandable cells and a plurality of longitudinal bars, the valve support configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is positioned in situ, said valve support supporting the base and the commissure points of the valve, wherein the commissure points of the valve are secured to the valve support at the longitudinal bars and adjacent one or more of the expandable cells.    
     
     
         69 . The valve assembly of  claim 68 , wherein the valve support is self-expanding.  
     
     
         70 . The valve assembly of  claim 68 , wherein the valve support is balloon expandable.  
     
     
         71 . The valve assembly of  claim 68 , wherein the valve support is configured to press radially against the native valve leaflets to hold the native valve leaflets against walls of the native valve annulus and/or against walls of an adjacent lumen to thereby prevent the native valve leaflets from obstructing the native valve annulus.  
     
     
         72 . The valve assembly of  claim 68 , wherein the longitudinal bars of the valve support further comprise a plurality of holes, wherein the plurality of leaflets are secured to the longitudinal bars via suture lines passing through the plurality of holes.