US2008015249A1PendingUtilityA1

Cancer treatment compositions and method using natural plant essential oils

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Assignee: ECOSMART TECHNOLOGIES INCPriority: Dec 7, 1998Filed: Aug 31, 2007Published: Jan 17, 2008
Est. expiryDec 7, 2018(expired)· nominal 20-yr term from priority
Inventors:Steven M. BessetteEssam Enan
A61P 43/00A61P 35/00A61P 15/14A61K 36/53A61K 38/45A61K 45/06A61K 31/122A61K 31/085A61K 36/00A61K 36/61A61K 36/898A61K 31/185A61K 31/05
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Claims

Abstract

Pharmaceutical compositions containing plant essential oils, natural or synthetic, or mixtures or derivatives thereof, for the prevention and treatment of soft tissue cancer in mammals.

Claims

exact text as granted — not AI-modified
1 - 13 . (canceled)  
   
   
       14 . A method for treating breast cancer in a patient in need thereof, the method comprising: 
 administering to the patient a therapeutically effective amount of a composition comprising a pharmaceutically acceptable carrier and an active ingredient comprising at least one plant essential oil compound selected from the group consisting of aldehyde C16 (pure), amyl cinnamic aldehyde, amyl salicylate, anisic aldehyde, benzyl alcohol, benzyl acetate, cinnamaldehyde, cinnamic alcohol, α-terpineol, carvacrol, carveol, citral, citronellal, citronellol, p-cymene, diethyl phthalate, dimethyl salicylate, dipropylene glycol, eucalyptol (cineole), iso-eugenol, galaxolide, geraniol, guaiacol, ionone, d-limonene, menthol, methyl anthranilate, methyl ionone, methyl salicylate, α-phellandrene, pennyroyal oil, perillaldehyde, 1- or 2-phenyl ethyl alcohol, 1- or 2-phenyl ethyl propionate, piperonal, piperonyl acetate, piperonyl alcohol, D-pulegone, terpinen-4-ol, terpinyl acetate, 4-tert butylcyclohexyl acetate, thyme oil, thymol, metabolites of trans-anethole, vanillin, and ethyl vanillin.    
   
   
       15 . The method of  claim 14 , wherein the plant essential oil compound is thymol.  
   
   
       16 . The method of  claim 14 , wherein the plant essential oil compound is isoeugenol.  
   
   
       17 . The method of  claim 14 , wherein the plant essential oil compound is benzyl alcohol.  
   
   
       18 . The method of  claim 14 , wherein the plant essential oil compound is carvacrol.  
   
   
       19 . The method of  claim 14 , wherein the plant essential oil compound is cinnamic alcohol.  
   
   
       20 . The method of  claim 14 , wherein the plant essential oil compound is cinnamic aldehyde.  
   
   
       21 . The method of  claim 14 , wherein the plant essential oil compound is citronellal.  
   
   
       22 . The method of  claim 14 , wherein the plant essential oil compound is trans-anethole.  
   
   
       23 . A method for inhibiting the growth of breast cancer cells, the method comprising a step of applying to the breast cancer cells a growth inhibiting amount of a plant essential oil compound to a population of the breast cancer cells for a sufficient time to observe inhibition of growth in said breast cancer cells.  
   
   
       24 . The method of  claim 23 , wherein the breast cancer cells are MCF-7 cells.  
   
   
       25 . The method of  claim 23 , wherein the plant essential oil compound is selected from the group consisting of aldehyde C16 (pure), amyl cinnamic aldehyde, amyl salicylate, anisic aldehyde, benzyl alcohol, benzyl acetate, cinnamaldehyde, cinnamic alcohol, α-terpineol, carvacrol, carveol, citral, citronellal, citronellol, p-cymene, diethyl phthalate, dimethyl salicylate, dipropylene glycol, eucalyptol (cineole), iso-eugenol, galaxolide, geraniol, guaiacol, ionone, d-limonene, menthol, methyl anthranilate, methyl ionone, methyl salicylate, α-phellandrene, pennyroyal oil, perillaldehyde, 1- or 2-phenyl ethyl alcohol, 1- or 2-phenyl ethyl propionate, piperonal, piperonyl acetate, piperonyl alcohol, D-pulegone, terpinen-4-ol, terpinyl acetate, 4-tert butylcyclohexyl acetate, thyme oil, thymol, metabolites of trans-anethole, vanillin, and ethyl vanillin.  
   
   
       26 . The method of  claim 23 , wherein the plant essential oil compound is thymol.  
   
   
       27 . The method of  claim 23 , wherein the plant essential oil compound is isoeugenol.  
   
   
       28 . The method of  claim 23 , wherein the plant essential oil compound is benzyl alcohol.  
   
   
       29 . The method of  claim 23 , wherein the plant essential oil compound is carvacrol.  
   
   
       30 . The method of  claim 23 , wherein the plant essential oil compound is cinnamic alcohol.  
   
   
       31 . The method of  claim 23 , wherein the plant essential oil compound is cinnamic aldehyde.  
   
   
       32 . The method of  claim 23 , wherein the plant essential oil compound is citronellal.

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