Chromatographic separation member and method

Abstract

There is described a chromatographic separation member including a substrate carrying on at least one surface a thin layer of a chromatographically active capture material. Also described is a chromatographic separation method for separating a component of interest from a fluid utilizing the chromatographic separation member.

1 . A chromatographically active separation member comprising 
 a) a substrate having first and second opposed surfaces; and    b) a dry continuous film of a chromatographically active functional polymeric material carried by said first surface.    
     
     
         2 . The chromatographically active separation member as defined in  claim 1  wherein said continuous film has a substantially uniform thickness.  
     
     
         3 . The chromatographically active separation member as defined in  claim 1  wherein said continuous film has a thickness of from about 0.25μ to about 3.0μ 
     
     
         4 . The chromatographically active separation member as defined in  claim 1  wherein said continuous film has a substantially non-uniform thickness and is arranged in a pattern.  
     
     
         5 . The chromatographically active separation member as defined in  claim 1  and further including a continuous film of a chromatographically active functional polymeric material carried by said second surface  
     
     
         6 . The chromatographically active separation member as defined in  claim 5  wherein said chromatographically active functional polymeric material carried by said first surface and by said second surface are the same.  
     
     
         7 . The chromatographically active separation member as defined in  claim 1  wherein said separation member further includes a layer of a hydrophilic polymer adhered to said first surface of said substrate and wherein said continuous film of chromatographically active functional polymeric material is deposited on said hydrophilic polymer layer.  
     
     
         8 . The chromatographically active separation member as defined in  claim 1  wherein said chromatographically active functional polymeric material is cross-linked to said substrate.  
     
     
         9 . The chromatographically active separation member as defined in  claim 7  wherein said chromatographically active functional polymeric material is cross-linked to said substrate.  
     
     
         10 - 18 . (canceled)  
     
     
         19 . The separation member as defined in  claim 1  wherein said member comprises a continuous endless web.