Central Nervous System Administration of Medications by Means of Pelvic Venous Catheterization and Reversal of Batson's Plexus

Abstract

An infusor system for administering medications to a venous blood vessel in the body of a patient. The infusor system includes a flexible, elongated delivery tube having opposite ends. One of the ends is couplable to a supply of liquid medication, which is remote from the venous blood vessel. The system further includes a delivery component coupled to the other end of the delivery tube. This delivery component is adaptable to be placed in confronting relationship with the venous blood vessel so that medication from said supply may be introduced directly into the venous blood vessel and distributed in the body of the patient. The infusor system further includes a pressure-altering device used for increasing intraabdominal pressure in the body of the patient.

1 . An infusor system for administering medications to a venous blood vessel in the: body of a patient comprising: 
 a flexible, elongated delivery tube having opposite ends, one of said ends couplable to a supply of liquid medication, said supply being remote from a venous blood vessel chosen from a pudic vein, an internal pudic vein, and an external pudic vein;    a delivery component coupled to the other of said ends, said delivery component adaptable to be placed in confronting relationship with said venous blood vessel so that medication from said supply may be introduced directly into said venous blood vessel and distributed in the body of the patient; and    a pressure-altering device, the pressure-altering device being positionable on the patient body for increasing pressure within the body of the patient to cause reversal of blood flow in Batson's Plexus to thereby delivery medication via said reversal of blood flow.    
   
   
       2 . The infusor system of  claim 1 , wherein said delivery component is selected from the group consisting of a venous needle and an indwelling venous catheter.  
   
   
       3 . The infusor system of  claim 1 , wherein said delivery component is adapted to be placed in confronting relationship with a venous blood vessel of the superficial or sacral venous system of the human body.  
   
   
       4 . The infusor system of  claim 3 , wherein said venous blood vessel is selected from the group consisting of a femoral vein, a deep epigastric vein, a deep circumflex iliac vein, an internal iliac vein, an internal pubic vein, a common iliac vein, a spermatic vein, a dorsal vein of the penis, an inguinal vein, a pudendal vein, a pubic vein, and a genitofemoral vein.  
   
   
       5 . The infusor system of  claim 1 , wherein said supply of liquid medication further includes an apparatus adapted to store said supply of liquid medication and/or deliver said supply of liquid medication to said tube, the apparatus being selected from the group consisting of an IV bag and a pump.  
   
   
       6 . The infusor system of  claim 1 , further comprising an injection site operatively connected to said tube for receiving a syringe for injecting bolus dosages of medication into said tube.  
   
   
       7 . The infusor system of  claim 1 , wherein said tube further includes a valve for allowing flow of said liquid medication in only one direction in said tube from said supply of liquid medication to said delivery component.  
   
   
       8 . The infusor system of  claim 1 , wherein said liquid medication is selected from the group consisting of chemotherapeutic medications, steroids, anesthetics, opioids, narcotic analgesics, and non-narcotic analgesics.  
   
   
       9 . The infusor system of  claim 1 , wherein said pressure to be increased in the patient body is intraabdominal pressure.  
   
   
       10 . The infusor system of  claim 9 , wherein said pressure-altering device is selected from the group consisting of an abdominal binder and an abdominal restraint.  
   
   
       11 . The infusor system of  claim 9 , wherein said intraabdominal pressure is increased to at least 30 mmHg.  
   
   
       12 . The infusor system of  claim 9 , wherein said intraabdominal pressure is in a range of about 15 mm Hg to about 90 mmHg.