US2008076752A1PendingUtilityA1
Novel Lactams And Uses Thereof
Est. expiryOct 3, 2022(expired)· nominal 20-yr term from priority
Inventors:Christopher BeckerBruce T. DembofskyRobert T. JacobsJames KangCyrus J. OhnmachtJames RosamondAshokkumar B. ShenviThomas SimpsonJames Woods
A61P 43/00A61P 25/28C07K 5/06034C07D 417/12A61P 25/00C07K 5/06191C07D 223/16C07D 267/14C07D 417/14C07D 405/04C07D 267/10C07K 5/06026C07D 281/06A61K 38/00C07D 281/10
57
PatentIndex Score
0
Cited by
0
References
0
Claims
Abstract
Compounds having the formula (I) pharmaceutical compositions containing them and their methods of use for the treatment of neurological disorders related to amyloid β protein production and neurological disorders such as Alzheimer's disease. These compounds inhibit γ secretase and thereby inhibit the production of amyloid β protein, thereby acting to prevent the formation of neurological deposits of amyloid protein.
Claims
exact text as granted — not AI-modified1 - 30 . (canceled)
31 . A pharmaceutical composition comprising a compound that functions to inhibit γ secretase comprising a substituted structure of 6-amino-7-phenyl-1,4-thiazepan-5-one.
32 . A pharmaceutical composition comprising a compound that functions to inhibit γ secretase comprising a substituted structure of 3-amino-2-(2,5-difluorophenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one.
33 . A pharmaceutical composition comprising a compound that functions to inhibit γ secretase comprising a substituted structure of 3-amino-2-phenyl-2,3-dihydro-1,5-benzoxazepin-4(5H)-one.Cited by (0)
No later patents cite this yet.
References (0)
No backward citations on record.