US2008107635A1PendingUtilityA1
Selection and use of lactic acid bacteria for reducing inflammation in mammals
Est. expiryApr 15, 2025(expired)· nominal 20-yr term from priority
Inventors:Eamonn Connolly
A61P 37/06A61P 37/00A61K 38/164Y10S435/853A61P 1/00A61P 1/04A61K 2035/11C12N 1/00C12N 1/20A61K 35/74C12R 2001/225C12N 1/205Y02A50/30
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Claims
Abstract
Strains of lactic acid bacteria selected for their capability of reducing inflammation, such as intestinal bowel disease, a method of selecting such strains, and products containing such strains
Claims
exact text as granted — not AI-modified1 . (canceled)
2 . (canceled)
3 . A method for selecting a bacterial strain effective for treating inflammation in inflammatory bowel disease, comprising: using THP-1 monocytic cell line from a human source, to identify a strain which is effective in decreasing TNFα.
4 . A method for treating inflammation in inflammatory bowel disease, comprising administering cells of a bacterial strain selected according to claim 3 .
5 . (canceled)
6 . A product for administration to a patient with inflammatory bowel disease comprising conditioned medium from a culture of a bacterial strain selected according to claim 3 .
7 . A product for administration to a patient with inflammatory bowel disease comprising a culture of a bacterial strain selected according to claim 3.Cited by (0)
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