US2008107635A1PendingUtilityA1

Selection and use of lactic acid bacteria for reducing inflammation in mammals

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Assignee: CONNOLLY EAMONNPriority: Apr 15, 2005Filed: Dec 24, 2007Published: May 8, 2008
Est. expiryApr 15, 2025(expired)· nominal 20-yr term from priority
Inventors:Eamonn Connolly
A61P 37/06A61P 37/00A61K 38/164Y10S435/853A61P 1/00A61P 1/04A61K 2035/11C12N 1/00C12N 1/20A61K 35/74C12R 2001/225C12N 1/205Y02A50/30
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Claims

Abstract

Strains of lactic acid bacteria selected for their capability of reducing inflammation, such as intestinal bowel disease, a method of selecting such strains, and products containing such strains

Claims

exact text as granted — not AI-modified
1 . (canceled)  
     
     
         2 . (canceled)  
     
     
         3 . A method for selecting a bacterial strain effective for treating inflammation in inflammatory bowel disease, comprising: using THP-1 monocytic cell line from a human source, to identify a strain which is effective in decreasing TNFα.  
     
     
         4 . A method for treating inflammation in inflammatory bowel disease, comprising administering cells of a bacterial strain selected according to  claim 3 .  
     
     
         5 . (canceled)  
     
     
         6 . A product for administration to a patient with inflammatory bowel disease comprising conditioned medium from a culture of a bacterial strain selected according to  claim 3 .  
     
     
         7 . A product for administration to a patient with inflammatory bowel disease comprising a culture of a bacterial strain selected according to  claim 3.

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