US2008112932A1PendingUtilityA1
Methods and reagents for the enhancement of virus transduction in the bladder epithelium
Est. expiryDec 26, 2022(expired)· nominal 20-yr term from priority
C12N 2710/10343A61P 35/04A61K 47/26A61P 35/00A61K 31/337A61K 47/10A61K 45/06A61K 35/761A61P 43/00C12N 7/00A61K 9/0019A61K 48/0083A61K 31/7024C12N 2710/10332A61K 48/00Y02A50/30
65
PatentIndex Score
0
Cited by
0
References
0
Claims
Abstract
Agents and methods for enhancing recombinant virus transduction in the bladder epithelium are described. A first method involves contacting the luminal surface of the bladder with a composition comprising a transduction enhancing agent and an oncolytic virus. Alternatively, the luminal surface of the bladder can be contacted first with a pretreatment composition comprising a transduction enhancing agent and, subsequently, with a composition comprising an oncolytic virus. Bladder treatment compositions comprising a transduction enhancing agent and an oncolytic virus are also described.
Claims
exact text as granted — not AI-modified1 . A method for treating cancer of the bladder comprising:
contacting the luminal surface of the bladder with a pretreatment composition comprising a transduction enhancing agent; and subsequently contacting the luminal surface of the bladder with a composition comprising an oncolytic virus; wherein the transduction enhancing agent is a mono-, di-, or polysaccharide having a lipophilic substituent.
2 - 95 . (canceled)Join the waitlist — get patent alerts
Track US2008112932A1 — get alerts on status changes and closely related new filings.
We store only your email — no account needed. See our privacy policy.