US2008119410A1PendingUtilityA1
Modulation of Pericyte Proliferation
Est. expiryDec 1, 2020(expired)· nominal 20-yr term from priority
A61P 37/00A61P 9/12A61P 3/10A61P 9/00A61P 9/10A61P 43/00A61P 27/02A61P 25/00A61P 25/28A61P 17/00G01N 33/5008G01N 33/5044A61P 19/08A61P 17/02A61P 21/00A61P 15/00A61P 11/00G01N 33/5011A61K 38/1751G01N 33/5017A61P 15/08G01N 33/5041
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Claims
Abstract
Methods and materials for modulating pericyte and epithelial cell proliferation relating to BPI protein products or inhibitors thereof are provided.
Claims
exact text as granted — not AI-modified1 . A method of enhancing pericyte cell proliferation comprising administering to a subject in need thereof an amount of a BPI protein product effective to enhance proliferation of pericyte cells.
2 - 4 . (canceled)
5 . The method of claim 1 wherein the subject is suffering from age related macular degeneration (ARMD).
6 - 19 . (canceled)
20 . The method of claim 1 wherein the BPI protein product is an amino-terminal fragment of BPI protein having a molecular weight of about 20 kD to 25 kD, or a dimeric form thereof.
21 . The method of claim 1 wherein the BPI protein product is a BPI-derived peptide.
22 . The method of claim 21 wherein the BPI-derived peptide is XMP.679.
23 - 34 . (canceled)
35 . A method of enhancing pericyte proliferation in a subject suffering from a pericyte degeneration disorder that is age related macular degeneration (ARMD), comprising administering to the subject an amount of a BPI protein product effective to enhance proliferation of pericytes.
36 - 39 . (canceled)Join the waitlist — get patent alerts
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