US2008139809A1PendingUtilityA1

Compounds Capable of Activating Cholinergic Receptors

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Assignee: CALDWELL WILLIAM SCOTTPriority: Jun 16, 1998Filed: Oct 31, 2007Published: Jun 12, 2008
Est. expiryJun 16, 2018(expired)· nominal 20-yr term from priority
Inventors:William Scott CaldwellGary Maurice DullBalwinder Singh BhattiSrishailkumar B. HadimaniHaeil ParkJared Miller WagnerPeter A. Crooks
A61P 25/28C07D 213/61C07D 213/38A61P 25/18A61K 31/44A61P 25/16C07D 213/73A61K 31/505C07D 213/65C07D 239/24C07D 239/26A61P 25/14
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Claims

Abstract

Compounds incorporating aryl substituted olefinic amine are provided. Representative compounds are (4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-pyrimidinyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-methoxy-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(6-amino-5-methyl-3-pyridyl)-4-penten-2-amine, (2R)-(4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (2R)-(4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-bromo-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-ethoxy-3-pyridyl)-4-penten-2-amine, (2S)-(4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine and (2S)-(4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine.

Claims

exact text as granted — not AI-modified
1 . A compound denoted (4E)-N-methyl-5-(5-pyrimidinyl)-4-penten-2-amine and pharmaceutically acceptable salts thereof.

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