Methods for accelerating wound healing by administration of adipokines

Abstract

Methods for inducing or accelerating a healing process of a damaged skin or skin wounds are described. The methods include administering to the skin cells colonizing the damaged skin or skin wound a therapeutically effective amount of an adipokine, an adipocyte or preadipocyte modulator, adipocytes, preadipocytes, or stem cells, or transforming the skin cells colonizing the damaged skin or skin wound such as to express and secrete an adipokine, thereby inducing or accelerating the healing process of the damaged skin or skin wound.

1 - 35 . (canceled) 
     
     
         36 . A method of inducing or accelerating a healing process of a damaged skin or skin wound, the method comprising administering to the skin cells colonizing the damaged skin or skin wound area a therapeutically effective amount of an agent selected from the group consisting of an adipokine, an adipocyte modulator and a preadipocyte modulator, thereby inducing or accelerating the healing process of the damaged skin or skin wound, wherein said agent is contained in a pharmaceutical composition adapted for topical or subcutaneous administration. 
     
     
         37 . The method of  claim 36 , wherein said topical pharmaceutical composition is selected from the group consisting of an aqueous solution, a gel, a cream, a paste, a lotion, a spray, a suspension, a powder, a dispersion, a salve and an ointment. 
     
     
         38 . The method of  claim 37 , wherein said pharmaceutical composition includes a solid support.