T Cell Apoptosis Inducer

Abstract

An inducer of T cell apoptosis and a health food for inducing T cell apoptosis comprising as an active ingredient of a lactic acid bacterium belonging to the genus Lactobacillus or the genus Bifidobacterium are disclosed. Particularly preferred lactic acid bacteria belonging to the genus Lactobacillus or the genus Bifidobacterium are Lactobacillus acidophilus L-92 (FERM BP-4981), Lactobacillus amylovorus CP1750 (FERM BP-10532), Bifidobacterium catenulatum CP2829 (FERM BP-10533) and Bifidobacterium longum CP760 (FERM BP-10531). The inducer of T cell apoptosis of the invention is useful in the prevention and cure of a disease such as an organ-specific autoimmune disease or type I allergy.

1 . An inducer of T cell apoptosis comprising as an active ingredient a lactic acid bacterium belonging to the genus Lactobacillus or the genus  Bifidobacterium.    
     
     
         2 . The inducer of T cell apoptosis according to  claim 1 , wherein the lactic acid bacterium belonging to the genus  Lactobacillus  is a lactic acid bacterium selected from the group consisting of  Lactobacillus acidophilus  and  Lactobacillus amylovorus.    
     
     
         3 . The inducer of T cell apoptosis according to  claim 1 , wherein the lactic acid bacterium belonging to the genus  Bifidobacterium  is a lactic acid bacterium selected from the group consisting of  Bifidobacterium catenulatum  and  Bifidobacterium longum.    
     
     
         4 . The inducer of T cell apoptosis according to  claim 1 , wherein the lactic acid bacterium is a lactic acid bacterium selected from the group consisting of  Lactobacillus acidophilus  L-92 (FERM BP-4981),  Lactobacillus amylovorus  CP1750 (FERM BP-10532), Bifidobacterium catenulatum CP2829 (FERM BP-10533) and  Bifidobacterium longum  CP760 (FERM BP-10531). 
     
     
         5 . A health food for inducing T cell apoptosis comprising a lactic acid bacterium belonging to the genus  Lactobacillus  or the genus  Bifidobacterium.    
     
     
         6 . The health food for inducing T cell apoptosis according to  claim 5 , wherein the lactic acid bacterium is a lactic acid bacterium selected from the group consisting of  Lactobacillus acidophilus  L-92 (FERM BP-4981),  Lactobacillus amylovorus  CP1750 (FERM BP-10532),  Bifidobacterium catenulatum  CP2829 (FERM BP-10533) and  Bifidobacterium longum  CP760 (FERM BP-10531). 
     
     
         7 . A novel lactic acid bacterium,  Lactobacillus amylovorus  CP1750 (FERM BP-10532). 
     
     
         8 . A novel lactic acid bacterium,  Bifidobacterium catenulatum  CP2829 (FERM BP-10533). 
     
     
         9 . A novel lactic acid bacterium,  Bifidobacterium longum  CP760 (FERM BP-10531).