Neuronal serine threonine protein kinase

Abstract

The present invention relates to a gene and the coded protein thereof that is involved in the development of sequelae of local ischaemia. The new protein is a serine threonine protein kinase and provides a new therapeutic approach to the prophylaxis and therapy of apoplexy.

1 - 30 . (canceled) 
     
     
         31 . An isolated nucleic acid that codes for a neuronal serine threonine protein kinase, selected from the group consisting of:
 a) a nucleic acid comprising SEQ ID NO: 3;   b) a nucleic acid that codes for a protein comprising SEQ ID NO: 7; and   c) a nucleic acid that codes for a protein having serine threonine kinase activity, said protein exhibits at least 90% identity to a protein comprising SEQ ID NO: 7.   
     
     
         32 . The nucleic acid according to claim  1  that codes for a protein comprising SEQ ID NO: 7. 
     
     
         33 . The nucleic acid according to claim  1 , wherein the nucleic acid is a DNA. 
     
     
         34 . A nucleic acid construct comprising an isolated nucleic acid selected from the group consisting of:
 a) a nucleic acid comprising SEQ ID NO: 3;   b) a nucleic acid that codes for a protein comprising SEQ ID NO: 7; and   c) a nucleic acid that codes for a protein having serine threonine kinase activity, said protein exhibits at least 90% identity to a protein comprising SEQ ID NO: 7.   
     
     
         35 . A nucleic acid construct according to claim  4 , wherein the construct is present in a plasmid. 
     
     
         36 . An isolated protein selected from the group consisting of:
 a) a protein comprising SEQ ID NO: 7;   b) a protein having serine threonine kinase activity, wherein said protein exhibits at least 90% identity to a protein comprising SEQ ID NO: 7.   
     
     
         37 . The protein according to claim  6 , wherein said protein comprises SEQ ID NO:7. 
     
     
         38 . An antibody that specifically targets the protein according to claim  6 . 
     
     
         39 . An isolated protein selected from the group consisting of:
 a) a protein comprising SEQ ID NO: 8; and   b) a protein having serine threonine kinase activity, wherein said protein exhibits at least 90% identity to a protein comprising SEQ ID NO: 8.   
     
     
         40 . The protein according to claim  9 , wherein said protein comprises SEQ D NO:8. 
     
     
         41 . An antibody that specifically targets the protein according to claim  9 .