Diaminooxidase-Containing Pharmaceutical Compositions

Abstract

The present invention relates to pharmaceutical compositions, food supplement compositions and cosmetic compositions comprising diaminooxidase, and to the use thereof.

1 .- 18 . (canceled) 
     
     
         19 . A pharmaceutical composition for treating a histamine-induced disease, said composition comprising an effective amount of diaminooxidase and being provided in a form selected from the group consisting of a hydrogel, a gastric-juice-resistant pellet, a gastric-juice-resistant capsule and a tablet, for an application selected from the group consisting of epidermal, oral and peroral administration. 
     
     
         20 . A pharmaceutical composition as set forth in  claim 19 , wherein said composition is a food supplement composition and is provided in a form selected from the group consisting of a gastric-juice-resistant pellet, a gastric-juice-resistant capsule and a tablet. 
     
     
         21 . A pharmaceutical composition as set forth in  claim 19 , wherein said composition is a dietary foodstuff and is provided in a form selected from the group consisting of a gastric-juice-resistant pellet, a gastric-juice-resistant capsule and a tablet. 
     
     
         22 . A pharmaceutical composition as set forth in  claim 19 , wherein said composition is a cosmetic composition. 
     
     
         23 . A pharmaceutical composition as set forth in  claim 22  and provided in a form for a cosmetic application, such as a hydrogel. 
     
     
         24 . A pharmaceutical composition as set forth in  claim 19 , wherein said diaminooxidase is a diaminooxidase of non-plant origin. 
     
     
         25 . A pharmaceutical composition as set forth in  claim 24 , wherein said diaminooxidase is of animal origin. 
     
     
         26 . A pharmaceutical composition as set forth in  claim 25 , wherein said diaminooxidase of animal origin is derived from porcine kidney. 
     
     
         27 . A pharmaceutical composition as set forth in  claim 19 , wherein said diaminooxidase is of recombinant origin. 
     
     
         28 . A pharmaceutical composition as set forth in  claim 27 , wherein said diaminooxidase of recombinant origin is recovered from one of prokaryotic and eukaryotic cell cultures. 
     
     
         29 . A pharmaceutical composition as set forth in  claim 28 , wherein said prokaryotic cell cultures are bacterial cell cultures. 
     
     
         30 . A pharmaceutical composition as set forth in  claim 28 , wherein said eukaryotic cell cultures are selected from the group consisting of animal and yeast cell cultures. 
     
     
         31 . A method of treating a histamine-induced disease in a patient, comprising administering to said patient an effective amount of diaminooxidase, said diaminooxidase being provided in a form selected from the group consisting of a hydrogel, a gastric-juice-resistant pellet, a gastric-juice-resistant capsule and a tablet, for an application selected from the group consisting of epidermal, oral and peroral administration. 
     
     
         32 . A method as set forth in  claim 31 , wherein said histamine-induced disease is urticaria, such as chronic and acute urticaria. 
     
     
         33 . A method as set forth in  claim 31 , wherein said histamine-induced disease is a contact allergy and said diaminooxidase is provided as a hydrogel for epidermal application. 
     
     
         34 . A method as set forth in  claim 31 , wherein said histamine-induced disease is an atopic dermatitis. 
     
     
         35 . A method as set forth in  claim 31 , wherein said histamine-induced disease is scombrotoxism and said diaminooxidase is provided in a form selected from the group consisting of a gastric-juice-resistant pellet, a gastric-juice-resistant capsule and a tablet, for an application selected from the group consisting of oral and peroral administration. 
     
     
         36 . A method as set forth in  claim 31 , wherein said diaminooxidase is provided in a form selected from the group consisting of a gastric-juice-resistant pellet, a gastric-juice-resistant capsule and a tablet, for an application selected from the group consisting of oral and peroral administration so as to remove histamine from the gastro-intestinal tract of said patient. 
     
     
         37 . A method of treating a histamine-induced disease in a patient, comprising administering to said patient a an effective amount of diaminooxidase, said diaminooxidase being provided in a form selected from drops and a spray, so as to remove histamine from the bronchial system of said patient.