Formulations Based on 3-Iodo-2-Propynyl Butyl Carbamate

Abstract

Formulations in water suspension of microcapsules based on 3-iodo-2-propynyl butyl carbamate (IPBC) comprising (parts by weight): (a) 10-60 parts of polymeric microcapsules comprising inside them IPBC and a synergizing agent formed of one or more alkylbenzenes having a number of carbon atoms from 9 to 20: (2) 1-5 parts of one or more dispersants; (3) 1-20 parts of one or more excipients selected from thickeners, antifoam, antifreeze, in can preservative agents; (4) water to 100.

1 - 18 . (canceled) 
     
     
         19 . Formulations in aqueous suspension of microcapsules based on 3-iodo-2-propynyl butyl carbamate (IPBC) comprising (parts by weight):
 (1) 10-60 parts of polymeric microcapsules comprising in the microcapsules IPBC, and a synergizing agent formed of one or more alkylbenzenes, linear or branched having a number of carbon atoms from 9 to 20, preferably from 10 to 16;   (2) 1-5 parts of one or more dispersants;   (3) 1-20 parts of one or more excipients selected from thickeners, antifoam, antifreeze, antimould agents;   (4) water to 100.   
     
     
         20 . Formulations according to  claim 19 , wherein the microcapsules have sizes of 1-30 micron, preferably from 2 to 20 micron. 
     
     
         21 . Formulations according to  claim 19 , wherein the microcapsule polymer is a polymer insoluble in water obtainable by in situ interfacial polymerization, preferably a polymer obtained by polycondensation, more preferably a polymer not using formaldehyde as monomer. 
     
     
         22 . Formulations according to  claim 21 , wherein the polymer is selected from polyamides, polyesters, polyvinylalcohols, polyurethanes, polyurea, polylactic acid, more preferably polyurea. 
     
     
         23 . Formulations according to  claim 19 , wherein the synergizing agent has a boiling point in the range 165° C.-310° C., preferably it has a distillation range in the range 160°-180° C. or in the range 220°-290° C. 
     
     
         24 . Formulations according to  claim 23 , wherein the synergizing agent has a distillation range in the range 182°-202° C. or in the range 226°-284° C. 
     
     
         25 . Formulations according to  claim 19 , wherein the dispersant (component (2)) is generally selected from sodium ligninsulphonates, calcium ligninsulphonates, etapropo block polymers, sodium polycarboxylates, polyalkenyl pyrrolidone; preferably white solid dispersants. 
     
     
         26 . Formulations according to  claim 19 , wherein the excipients are: thickeners, preferably xanthan rubber; antifoam, preferably silicone compounds; antifreeze, preferably inorganic salts, more preferably calcium nitrate, sodium carbonate; in can preservative, preferably substituted triazines and benzoisothiazolinones. 
     
     
         27 . IPBC microcapsules according to  claim 19 . 
     
     
         28 . Formulations of microcapsules according to  claim 19 , obtainable according to the following process:
 a) preparation of a homogeneous IPBC mixture and one or more alkylbenzenes at a temperature in the range of about 15° C. and 70° C., preferably between 40° C. and 60° C., the ratio by weight IPBC/alkyl-benzenes ranging between 1:0.5 and 1:2, preferably between 1:1 and 1:1.5;   b) addition to the mixture obtained in a) of one or more water-insoluble monomers, precursors of the polymer forming the microcapsule, walls in amounts in the range 5-20% by weight, preferably 6-12% by weight with respect to the weight of the mixture obtained in a);   c) addition of the organic phase obtained in b) to an aqueous phase comprising at least one dispersant, in a ratio by weight aqueous phase/organic phase between 0.4:1 and 1:1, preferably between 0.6:1 and 0.9:1, thus obtaining an oil/water emulsion;   d) optional addition to the emulsion obtained in c) of the water-soluble monomers, precursors of the polymer forming the microcapsule, walls in a molar ratio 0.9-1, preferably 0.92-0.99 with respect to the monomers used in b);   e) heating at temperature in the range 50° C.-80° C., preferably 55° C.-70° C., to allow the formation of the polymeric membrane forming the microcapsule walls.   
     
     
         29 . Formulations according to  claim 28 , wherein the waterinsoluble monomers are polymethylene polyphenyl isocyanate (MDI) or MDI mixtures with toluene diisocyanate (TDI), when the polymer of the microencapsulated biocide is polyurea or polyurethane. 
     
     
         30 . Formulations according to  claim 28 , wherein the water-soluble monomers to be used in step d) are hexamethylendiamine, optionally in water solution, in case of polyurea microcapsules. 
     
     
         31 . A process for preparing the formulations of  claim 19  comprising:
 a) preparation of a homogeneous IPBC mixture and one or more alkylbenzenes at a temperature in the range of about 15° C. and 70° C., preferably between 40° C. and 60° C., the ratio by weight IPBC/alkyl-benzenes ranging between 1:0.5 and 1:2, preferably between 1:1 and 1:1.5;   b) addition to the mixture obtained in a) of one or more water-insoluble monomers, precursors of the polymer forming the microcapsule, walls in amounts in the range 5-20% by weight, preferably 6-12% by weight with respect to the weight of the mixture obtained in a);   c) addition of the organic phase obtained in b) to an aqueous phase comprising at least one dispersant, in a ratio by weight aqueous phase/organic phase between 0.4:1 and 1:1, preferably between 0.6:1 and 0.9:1, thus obtaining an oil/water emulsion;   d) optional addition to the emulsion obtained in c) of the water-soluble monomers, precursors of the polymer forming the microcapsule, walls in a molar ratio 0.9-1, preferably 0.92-0.99 with respect to the monomers used in b);   e) heating at temperature in the range 50° C.-80° C., preferably 55° C.-70° C., to allow the formation of the polymeric membrane forming the microcapsule walls.   
     
     
         32 . A process according to  claim 31 , wherein when the polymer forming the membrane is polyurea, the process comprising the following steps:
 a) preparation of a homogeneous IPBC mixture and one or more alkylbenzenes, under stirring, at a temperature in the range 25° C.-70° C., preferably 40° C.-60° C., the ratio by weight IPBC/alkylbenzenes ranges between 1:0.5 and 1:2, preferably between 1:1 and 1:1.5, maintaining under stirring until complete homogenization;   b) addition to the mixture obtained in a) of one water-insoluble monomer, precursor of the polyurea, preferably polymethylene polyphenyl isocyanate (MDI) or MDI mixtures with toluene diisocyanate (TDI), in amounts in the range 6-12% by weight with respect to the total weight of the mixture obtained in a), under stirring, maintaining substantially the same temperature of step a);   c) addition to an aqueous phase comprising at least one dispersant of the organic phase obtained in b), in a ratio by weight aqueous phase/organic phase between 0.6:1 and 0.9:1, under strong stirring, preferably by using a high “shear rate” stirrer, preferably having a speed higher than 5,000 rpm, more preferably of the Turrax type, for at least 3 minutes, thus obtaining an oil/water emulsion;   d) optional addition to the emulsion obtained in c) of a water-soluble monomer, precursor of the polyurea, preferably hexamethylendiamine, optionally in water solution, in a molar ratio 0.9-1, preferably 0.92-0.99 with respect to the isocyanate used in b), under stirring, preferably by using a low “shear rater” stirrer of the blade type, more preferably having a speed lower than 1,000 rpm;   e) completion of the polymerization reaction started in d) by maintaining the temperature in the range 50° C.-80° C., preferably 55° C.-60° C., for at least three hours.   
     
     
         33 . Use of the formulations of  claim 19  as biocides, as solvent-based or water-based formulations, preferably water-based compositions. 
     
     
         34 . Use of the formulations or of the microcapsules of  claim 19  as biocides for substrata, for paints, for coating products, for surfactants, for proteins, for starch-based compositions, for products for cosmetic use, for inks, for emulsions, for resins, for plasters, for cement surfaces, for wood, for leathers, for plastics, for textiles, for lubricants, for metal working fluids, for polymeric dispersions, for aqueous based products, for latexes containing polyvinyl alcohol, for polyacrylates or vinyl polymers, for thickening solutions containing cellulose derivatives, for kaolin-based suspensions, etc. 
     
     
         35 . Formulations in aqueous suspension of microcapsules and microcapsules according to  claim 19  wherein the microcapsules comprise inside them, in addition to the IPBC and the synergizing agent, a N-alkyl pyrrolidone, being the alkyl substituent a C 1 -C 18  alkyl, linear or branched, preferably C 6 -C 16 . 
     
     
         36 . Formulations in aqueous suspension of microcapsules and microcapsules according to  claim 19  wherein the
 synergizing agent is selected among biphenyl compounds,   preferably diisopropyl biphenyl isomers mixture (C 18 H 22 ).