US2008213197A1PendingUtilityA1

Agent for protection of tooth surfaces, in conjunction with conventional bleaching methods, by biomimetic deposition of fluorapatite

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Assignee: HERAEUS KULZER GMBHPriority: Nov 21, 2006Filed: Nov 19, 2007Published: Sep 4, 2008
Est. expiryNov 21, 2026(~0.3 yrs left)· nominal 20-yr term from priority
Inventors:Susanne BuschAndreas UtterodtMarcus HoffmannChristoph Maetzig
A61P 1/02A61K 2800/88A61K 8/24A61K 8/19A61K 8/042A61K 8/65A61K 8/0208A61Q 11/00
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Claims

Abstract

An agent for protection of tooth surfaces, in conjunction with conventional bleaching methods, by biomimetic deposition of fluorapatite, containing A at least one preformulated 50-1000 μm thick gel film A, containing A1 at least one gel former, A2 water or a mixture of water and an organic solvent, A3 phosphate or hydrogen phosphate ions, A4 optionally fluoride, A5 optionally at least one amino acid, A6 optionally one carboxylic acid or a buffer system for a pH value from 4 to 7. B at least one 50 μm to 5 mm thick gel film B, containing B1 at least one gel former, B2 water, B3 calcium ions Ca 2+ .

Claims

exact text as granted — not AI-modified
1 . Agent for protection of tooth surfaces, in conjunction with conventional bleaching methods, by biomimetic deposition of fluorapatite, comprising:
 A at least one preformulated 50-1000 μm thick gel film A, comprising:   A1 at least one gel former,   A2 water or a mixture of water and an organic solvent,   A3 phosphate or hydrogen phosphate ions,   A4 optionally fluoride,   A5 optionally at least one amino acid,   A6 optionally one carboxylic acid or a buffer system for a pH value from 4 to 7.   B at least one 50 μm to 5 mm thick gel film B, comprising:   B1 at least one gel former,   B2 water,   B3 calcium ions Ca 2+ .   
     
     
         2 . Agent according to  claim 1 , in which
 A3 0.01-2 mol per liter of gel of a phosphate or hydrogen phosphate is contained.   
     
     
         3 . Agent according to  claim 1 , in which
 B3 0.05 to 3 mol per liter of gel calcium ions Ca 2+  are contained.   
     
     
         4 . Agent according to  claim 1 , in which the gel former is gelatin. 
     
     
         5 . Agent according to  claim 4 , in which the gelatin concentration in A and B is 1-15 wt. % each. 
     
     
         6 . Agent according to  claim 5 , in which the gelatin concentration is 5-10 wt. %. 
     
     
         7 . Agent according to  claim 1 , in which the phosphate or hydrogen phosphate is present as dissociated Na 2 HPO 4  (NH 4 ) 2 HPO 4  or K 2 HPO 4 . 
     
     
         8 . Agent according to  claim 1 , in which the calcium ions are present as dissociated CaCl 2 .

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