Compositions containing capsinoids

Abstract

Problem to be Solved To provide a technique for allowing pulverization and water-solubilization of capsinoids while maintaining their stability. Solution Providing a composition comprising a capsinoid compound and cyclodextrin.

1 . A composition, comprising:
 (a) at least one capsinoid compound; and   (b) at least one cyclodextrin.   
     
     
         2 . A composition as claimed in  claim 1 , wherein said at least one capsinoid compound is one or more members selected from the group consisting of capsiate, dihydrocapsiate, nordihydrocapsiate, and a mixture thereof. 
     
     
         3 . A composition as claimed in  claim 1 , wherein said at least one cyclodextrin is one or more members selected from the group consisting of α-cyclodextrin, β-cyclodextrin, γ-cyclodextrin, and a mixture thereof. 
     
     
         4 . A composition as claimed in  claim 2 , wherein said at least one cyclodextrin is one or more members selected from the group consisting of α-cyclodextrin, β-cyclodextrin, γ-cyclodextrin, and a mixture thereof. 
     
     
         5 . A composition as claimed in  claim 1 , wherein:
 said at least one capsinoid compound is a mixture of capsiate, dihydrocapsiate, and nordihydrocapsiate; and   said at least one cyclodextrin is γ-cyclodextrin.   
     
     
         6 . A composition as claimed in  claim 1 , wherein:
 said at least one capsinoid compound is dihydrocapsiate; and   said at least one cyclodextrin is γ-cyclodextrin.   
     
     
         7 . A composition as claimed in  claim 1 , wherein said at least one capsinoid compound and said at least one cyclodextrin form a complex. 
     
     
         8 . A composition as claimed in  claim 2 , wherein said at least one capsinoid compound and said at least one cyclodextrin form a complex. 
     
     
         9 . A composition as claimed in  claim 3 , wherein said at least one capsinoid compound and said at least one cyclodextrin form a complex. 
     
     
         10 . A composition as claimed in  claim 1 , wherein said at least one capsinoid compound and said at least one cyclodextrin are present in a molar ratio of 2:1 to 1:2. 
     
     
         11 . A composition as claimed in  claim 2 , wherein said at least one capsinoid compound and said at least one cyclodextrin are present in a molar ratio of 2:1 to 1:2. 
     
     
         12 . A composition as claimed in  claim 3 , wherein said at least one capsinoid compound and said at least one cyclodextrin are present in a molar ratio of 2:1 to 1:2. 
     
     
         13 . A food composition, comprising a composition as claimed in  claim 1  and a cyclodextrin which does not form a complex. 
     
     
         14 . A process for making a composition, which comprises at least one capsinoid compound and at least one cyclodextrin,
 said process comprising:   (i) mixing at least one capsinoid compound with at least one cyclodextrin, to obtain a mixture; and   (ii) drying and pulverizing said mixture.   
     
     
         15 . A process as claimed in  claim 14 , which comprises mixing at least one capsinoid compound with at least one cyclodextrin in a molar ratio of 4:1 to 1:10. 
     
     
         16 . A method of treating obesity, comprising administering, to a subject in need thereof, an effective amount of a composition, comprising:
 (a) at least one capsinoid compound; and   (b) at least one cyclodextrin.   
     
     
         17 . A method as claimed in  claim 16 , wherein said at least one capsinoid compound is one or more members selected from the group consisting of capsiate, dihydrocapsiate, nordihydrocapsiate, and a mixture thereof. 
     
     
         18 . A method as claimed in  claim 16 , wherein said at least one cyclodextrin is one or more members selected from the group consisting of α-cyclodextrin, β-cyclodextrin, γ-cyclodextrin, and a mixture thereof. 
     
     
         19 . A method as claimed in  claim 18 , wherein said at least one cyclodextrin is one or more members selected from the group consisting of α-cyclodextrin, β-cyclodextrin, γ-cyclodextrin, and a mixture thereof. 
     
     
         20 . A method as claimed in  claim 16 , wherein:
 said at least one capsinoid compound is a mixture of capsiate, dihydrocapsiate, and nordihydrocapsiate; and said at least one cyclodextrin is γ-cyclodextrin.