US2008214812A1PendingUtilityA1

Trisubstituted triazolopyrimidines for use in platelet aggregation inhibition

Assignee: ASTRAZENECA ABPriority: Dec 4, 1998Filed: May 8, 2008Published: Sep 4, 2008
Est. expiryDec 4, 2018(expired)· nominal 20-yr term from priority
A61P 9/10A61P 7/02A61P 35/00A61P 7/00A61P 35/02A61P 9/00A61P 43/00A61P 25/06A61P 29/00A61P 25/00A61P 1/04A61P 11/00A61P 13/12C07D 487/04A61K 31/519C07C 211/40C07D 239/48
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Claims

Abstract

The invention provides new triazolo[4,5-d]pyrimidine compounds, their use as medicaments, compositions containing them and processes for their preparation.

Claims

exact text as granted — not AI-modified
1 - 18 . (canceled) 
     
     
         19 . A compound of formula (V): 
       
         
           
           
               
               
           
         
         where: 
         R 1  is propyl; 
         R 3  and R 4  are both hydroxy; or are protected derivatives thereof or R 3  and R 4  together form a bond in the 5-membered ring; 
         R is OCH 2 CH 2 OH; 
         and L is a leaving group. 
       
     
     
         20 . A compound according to  claim 19  in which L is halogen or SR. 
     
     
         21 . A process for the preparation of a compound of formula (V) as claimed in  claim 19  which comprises reducing a compound of formula (VI): 
       
         
           
           
               
               
           
         
         where: 
         R 1  is propyl; 
         L is a leaving group; 
         P 1  and P 2  are protecting groups.

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