US2008227956A1PendingUtilityA1

Novel morphogenic protein compositions of matter

72
Assignee: STRYKER CORPPriority: Mar 11, 1991Filed: Jul 2, 2007Published: Sep 18, 2008
Est. expiryMar 11, 2011(expired)· nominal 20-yr term from priority
Inventors:William K. JonesRonald TuckerDavid C. RuegerHermann OppermannEngin OzkaynakThangavel Kuberasampath
A61K 6/20A61K 38/17G01N 2500/10Y10S436/815A61F 2310/00365A23C 9/20A61L 27/24C07K 16/22Y10S436/811Y10S435/975A61K 38/1703A23L 33/19G01N 33/6893A61L 27/227C07K 14/495C07K 14/51A61K 38/1875A61K 48/00
72
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

Disclosed are novel compositions of morphogenic proteins constituting soluble forms of these proteins, antibodies that distinguish between soluble and mature forms, and method for producing these morphogenic proteins and antibodies.

Claims

exact text as granted — not AI-modified
1 - 25 . (canceled) 
     
     
         26 . An isolated peptide comprising residues 30-290 of SEQ ID NO: 17, wherein said peptide solubilizes a morphogen under physiological conditions when said morphogen is mixed with said peptide. 
     
     
         27 . The isolated peptide of  claim 26 , wherein said morphogen is BMP-3. 
     
     
         28 . A method for solubilizing a morphogen comprising the step of mixing the isolated peptide of  claim 26  with a morphogen, wherein said morphogen is BMP-3. 
     
     
         29 . An isolated peptide comprising residues 30-374 of SEQ ID NO: 16, wherein said peptide solubilizes a morphogen under physiological conditions when said morphogen is mixed with said peptide. 
     
     
         30 . The isolated peptide of  claim 29 , wherein said morphogen is BMP-6. 
     
     
         31 . A method for solubilizing a morphogen comprising the step of mixing the isolated peptide of  claim 29  with a morphogen, wherein said morphogen is BMP-6. 
     
     
         32 . An isolated peptide comprising residues 30-316 of SEQ ID NO: 18, wherein said peptide solubilizes a morphogen under physiological conditions when said morphogen is mixed with said peptide. 
     
     
         33 . The isolated peptide of  claim 32 , wherein said morphogen is BMP-5. 
     
     
         34 . A method for solubilizing a morphogen comprising the step of mixing the isolated peptide of  claim 32  with a morphogen, wherein said morphogen is BMP-5.

Join the waitlist — get patent alerts

Track US2008227956A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.