US2008241213A1PendingUtilityA1

Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof

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Assignee: CHUN IKSOOPriority: Mar 7, 2003Filed: Mar 31, 2008Published: Oct 2, 2008
Est. expiryMar 7, 2023(expired)· nominal 20-yr term from priority
Inventors:Iksoo ChunDennis D. JamiolkowskiKelly R. BrownJulia HwangFrancois BinetteMora Melican
A61F 2/08A61L 27/48A61L 27/46A61F 2210/0004A61L 2430/34A61L 27/446A61L 27/56
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Claims

Abstract

A biocompatible tissue implant. The tissue implant may be bioabsorbable, and is made from a biocompatible polymeric foam. The tissue implant also includes a biocompatible reinforcement member. The polymeric foam and the reinforcement member are soluble in a common solvent.

Claims

exact text as granted — not AI-modified
1 . A tissue implant, comprising a biocompatible polymeric foam and a biocompatible polymeric reinforcement member, wherein the foam and the reinforcement member are soluble in a common solvent. 
     
     
         2 . The implant of  claim 1 , wherein the polymeric foam is bioabsorbable. 
     
     
         3 . The implant of  claim 1 , wherein the polymeric foam comprises a polymer selected from the group consisting of aliphatic polyesters, poly(amino acids), polyalkylenes oxalates, polyamides, tyrosine derived polycarbonates, polyorthoesters, polyoxaesters, polyamidoesters, and copolymers and blends thereof. 
     
     
         4 . The implant of  claim 1 , wherein the polymeric foam comprises poly(lactide-co-caprolactone) having a mole ratio of between about 70/30 and about 55/45. 
     
     
         5 . The implant of  claim 1 , wherein the polymeric foam comprises poly(lactide-co-caprolactone) having a mole ratio of about 60/40. 
     
     
         6 . The implant of  claim 1 , wherein the polymeric foam comprises poly(glycolide-co-caprolactone) having a mole ratio of between 35/65 and 65/35. 
     
     
         7 . The implant of  claim 1 , wherein the polymeric foam comprises poly(glycolide-co-caprolactone) having a mole ratio of about 65/35. 
     
     
         8 . The implant of  claim 1 , wherein the polymeric foam comprises a blend of poly(lactide-co-caprolactone) having a mole ratio of about 60/40 and poly(glycolide-co-caprolactone) having a mole ratio of about 65/35. 
     
     
         9 . The implant of  claim 1 , wherein the polymeric reinforcement member comprises a plurality of particles. 
     
     
         10 . The implant of  claim 1 , wherein the polymeric reinforcement member comprises at least one sheet. 
     
     
         11 . The implant of  claim 1 , wherein the polymeric reinforcement member comprises at least one fiber. 
     
     
         12 . The implant of  claim 11 , wherein the fiber comprises a monofilament. 
     
     
         13 . The implant of  claim 11 , wherein the fiber comprises a multifilament yarn. 
     
     
         14 . The implant of  claim 13 , wherein the yarn comprises at least two filaments. 
     
     
         15 . The implant of  claim 11 , wherein the fiber comprises a mesh. 
     
     
         16 . The implant of  claim 11 , wherein the fiber comprises a braid. 
     
     
         17 . The implant of  claim 11 , wherein the fiber comprises a surgical suture. 
     
     
         18 . The implant of  claim 11 , wherein the fiber comprises a weave. 
     
     
         19 . The implant of  claim 11 , wherein the fiber comprises a knit. 
     
     
         20 . The implant of  claim 11 , wherein the fiber comprises a non-woven. 
     
     
         21 . The implant of  claim 15  wherein the mesh comprises a monofilament. 
     
     
         22 . The implant of  claim 16 , wherein the braid comprises a monofilament. 
     
     
         23 . The implant of  claim 12 , wherein the monofilament has a diameter between about 50 and about 2000 micron. 
     
     
         24 . The implant of  claim 14 , wherein the mesh has a mesh density of about 20% to about 88%. 
     
     
         25 . The implant of  claim 14 , wherein the mesh has a mesh density of about 20% to about 55%. 
     
     
         26 . The implant of  claim 1 , wherein the polymeric reinforcement member comprises a bioabsorbable polymer. 
     
     
         27 . The implant of  claim 1 , wherein the polymeric reinforcement member comprises a polymer selected from the group consisting of aliphatic polyesters, poly(amino acids), polyalkylenes oxalates, polyamides, tyrosine derived polycarbonates, polyorthoesters, polyoxaesters, polyamidoesters, and copolymers blends thereof. 
     
     
         28 . The implant of  claim 1 , wherein the polymeric reinforcement member comprises a mesh, said mesh comprising a copolymer of polymerized lactide and glycolide. 
     
     
         29 . The implant of  claim 1 , wherein the polymeric reinforcement member comprises a mesh, said mesh comprising poly(lactide-co-glycolide) at a 95/5 mole ratio. 
     
     
         30 . The implant of  claim 1 , wherein the foam comprises an open cell structure. 
     
     
         31 . The implant of  claim 1  wherein the foam comprises a closed cell structure. 
     
     
         32 - 60 . (canceled)

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