US2008249503A1PendingUtilityA1

Methods and devices for lung treatment

56
Individually held — no corporate assignee on recordPriority: Mar 8, 2002Filed: Jun 4, 2008Published: Oct 9, 2008
Est. expiryMar 8, 2022(expired)· nominal 20-yr term from priority
Inventors:Antony J. FieldsRonald HundertmarkJohn Mccutcheon
A61F 2/2418A61F 2/2427A61F 2/91A61F 2002/043A61F 2/2412A61F 2/06A61F 2/04F16K 15/147A61B 17/00491
56
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Claims

Abstract

A method of treating a lung comprises deploying a delivery catheter through a bronchial tree into a targeted lung region and delivering a fibrinogen suspension through the delivery catheter so that the fibrinogen suspension exits the distal end of the delivery catheter into the targeted lung region. Thrombin is also delivered through the delivery catheter so that the thrombin exits the distal end of the delivery catheter into the targeted lung region. The lung is promoted to collapse.

Claims

exact text as granted — not AI-modified
1 . A method of treating a lung, comprising:
 deploying a delivery catheter through a bronchial tree into a targeted lung region such that a distal end of the delivery catheter is positioned at or near the targeted lung region;   delivering a fibrinogen suspension through the delivery catheter so that the fibrinogen suspension exits the distal end of the delivery catheter into the targeted lung region, wherein the fibrinogen suspension comprises fibrinogen and poly-L-lysine;   delivering thrombin through the delivery catheter so that the thrombin exits the distal end of the delivery catheter into the targeted lung region;   causing the fibrinogen suspension and the thrombin to mix; and   promoting the lung to collapse.   
   
   
       2 . A method as in  claim 1 , wherein the fibrinogen suspension is delivered prior to delivering the thrombin. 
   
   
       3 . A method as in  claim 1 , wherein the thrombin is delivered prior to delivering the fibrinogen suspension. 
   
   
       4 . A method as in  claim 1 , further comprising mixing the fibrinogen suspension and the thrombin prior to delivering the fibrinogen suspension and the thrombin through the delivery catheter. 
   
   
       5 . A method as in  claim 1 , wherein the fibrinogen suspension further comprises chondroitin sulfate. 
   
   
       6 . A method as in  claim 1 , wherein the fibrinogen suspension further comprises tetracycline. 
   
   
       7 . A method as in  claim 1 , further comprising:
 puncturing a bronchial wall of a bronchial passageway located near the targeted lung region;   passing the distal end of the delivery catheter through the bronchial wall into the target lung region; and   causing the fibrinogen suspension or the thrombin to exit the distal end of the delivery catheter into the targeted lung region.   
   
   
       8 . A method as in  claim 1 , wherein the delivery catheter is a bronchoscope. 
   
   
       9 . A method as in  claim 1 , wherein the delivery catheter has at least two lumens. 
   
   
       10 . A method as in  claim 1 , wherein the fibrinogen suspension and the thrombin are delivered simultaneously through the delivery catheter.

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