US2008255234A1PendingUtilityA1

Rumen protected lysine

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Assignee: ZINPRO CORPPriority: Apr 11, 2007Filed: Apr 11, 2007Published: Oct 16, 2008
Est. expiryApr 11, 2027(~0.7 yrs left)· nominal 20-yr term from priority
A61P 1/00A61P 1/14A23K 50/10A23V 2002/00A23K 20/142
55
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Claims

Abstract

Use of lysine imines and compositions containing them as a source of rumen protected lysine for ruminant animals.

Claims

exact text as granted — not AI-modified
1 . A composition for supplementing the diet of ruminants with a source of rumen protected lysine comprising:
 a non toxic carrier; and   a diet supplementing effective amount of a lysine imine of the formula:   
       
         
           
           
               
               
           
         
         wherein R 1  and R 2  can be the same or different and are selected from the group consisting of hydrogen, aliphatic, aromatics, and cyclic moieties, R 3  and R 4  can be the same or different and are selected from the group consisting of hydrogen, aliphatic, aromatic and carbonyl moieties, and where R 3  is carbonyl, R 4  is not present and R 5  can be —OH, an ester producing moiety, or an inorganic salt producing moiety or amide producing moiety. 
       
     
     
         2 . The composition of  claim 1  wherein R 1 , R 3 , and R 4  are hydrogen and R 2  is formed from use as a reactant Benzaldehyde, Salicylaldehyde, Cinnamaldehyde or Vanillin and R 5  is —OH. 
     
     
         3 . The composition of  claim 1  wherein R 1 , R 3 , and R are hydrogen and R 2  is formed from use as a reactant butyrlaldehyde, isobutylylaldehyde, propionaldehyde or octylaldehyde and R 5  is —OH. 
     
     
         4 . The composition of  claim 1  wherein R 1  and R 2  are formed from use as a reactant Cyclohexanone, propiophenone, diethylketone, octanone, decanone or acetone. 
     
     
         5 . The composition of  claim 2  wherein R 3 , R 4  are hydrogen and R 5  is either an organic moiety to form an ester or an inorganic salt moiety. 
     
     
         6 . The composition of  claim 1  wherein the non-toxic carrier is a flavorant. 
     
     
         7 . The composition of  claim 1  wherein the nontoxic carrier is selected from the group consisting of sugars, fermentations solubles, feed grains, corn cob flour, whey, and other cellulosic carrier materials. 
     
     
         8 . The composition of  claim 1  wherein the diet supplementing effective amount is an amount sufficient to provide a level of from about 1 gr to about 50 gr of lysine used per animal per day. 
     
     
         9 . The method of providing rumen protected lysine for dietary supplementation of ruminants, said method comprising:
 selecting at least one lysine imine to be used as a source of rumen protected lysine.   
     
     
         10 . The method of  claim 9  wherein the lysine imine is at least one lysine imine of the formula: 
       
         
           
           
               
               
           
         
         wherein R 1  and R 2  can be the same or different and are selected from the group consisting of hydrogen, aliphatic, aromatics, and cyclic moieties, R 3  and R 4  can be the same or different and are selected from the group consisting of hydrogen, aliphatic, aromatic and carbonyl moieties, and where R 3  is carbonyl, R 4  is not present and R 5  can be —OH, an ester producing moiety, or an inorganic salt moiety or an amide producing moiety. 
       
     
     
         11 . The method of  claim 10  wherein R 1 , R 3 , and R 4  are hydrogen and R 2  is formed from use as a reactant Benzaldehyde, Salicylaldehyde, Cinnamaldehyde or Vanillin and R 5  is —OH. 
     
     
         12 . The method of  claim 1  wherein R 1 , R 3 , and R 4  are hydrogen and R 2  is formed from use as a reactant butyrlaldehyde, isobutylylaldehyde, propionaldehyde or octylaldehyde and R 5  is —OH. 
     
     
         13 . The method of  claim 10  wherein R 3 , R 4  are hydrogen and R 5  is either an organic moiety to form an ester or an inorganic moiety to form a salt. 
     
     
         14 . The method of  claim 10  wherein an additional step includes mixing the lysine imine with a non-toxic carrier as a flavorant. 
     
     
         15 . The method of  claim 14  wherein the nontoxic carrier is selected from the group consisting of sugars, fermentations solubles, feed grains, corn cob flour, whey, and other cellulosic carrier materials. 
     
     
         16 . The method of  claim 15  wherein a diet supplementing effective amount of said lysine imine is used and is an amount sufficient to provide a level of from about 1 gr to about 50 gr of lysine used per animal per day.

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