US2008293784A1PendingUtilityA1

Epothilones c, d, e and f, preparation and compositions

Assignee: HELMHOLTZ ZENTRUM FUR INFEKTIOPriority: Nov 18, 1996Filed: Apr 28, 2008Published: Nov 27, 2008

Est. expiryNov 18, 2016(expired)· nominal 20-yr term from priority

Inventors:Gerhard Hoefle Heinrich Steinmetz

A61P 43/00A61P 35/00A61P 35/04C07D 417/06C12P 17/167A01N 43/90A01N 43/78C07D 493/04C12P 17/181A01N 63/20

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Claims

Abstract

The present invention relates to epothilones C, D, E and F, their preparation and their use for the production of therapeutic compositions and compositions for plant protection.

Claims

exact text as granted — not AI-modified

1 - 16 . (canceled) 
   
   
       17 . A compound of the formula: 
     
       
         
         
             
             
         
       
     
     said compound having a state of purity such as to be substantially free of other major metabolic products produced by Sorangium cellulosum. 
   
   
       18 . A composition comprising at least one compound according to  claim 17 , and at least one carrier or diluent. 
   
   
       19 . A method of treating tumor comprising administering to a recipient in need thereof a therapeutic amount of a compound of the formula: 
     
       
         
         
             
             
         
       
     
     wherein said tumor is selected from the group consisting of leukemia, lymphoma, carcinoma of the cervix, carcinoma of the kidney and carcinoma of the lung.

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