Odourless garlic supplement comprising an enteric coating and a deodorising layer

Abstract

A garlic supplement comprises one or more cores comprising garlic and an enteric coating encasing the core(s) which is insoluble at pH less than about 5 but soluble at a pH greater than about 5. In one example, the enteric coating comprises a deodorizer. In another example, an external coating is present over the enteric coating and the external coating includes a deodorizer.

1 . A garlic supplement comprising:
 (a) one or more cores comprising garlic; and   (b) an enteric coating encasing the core(s) which is insoluble at pH less than about 5 but soluble at a pH greater than about 5 and wherein the enteric coating comprises a deodorizer.   
   
   
       2 . The garlic supplement according to  claim 1  wherein the deodorizer is selected from the group consisting of extracts, aqueous extracts, natural flavours or oils derived from parsley seed, Lamiaceae plants, green tea, and flavanoid containing plants or synthetic versions thereof and mixtures thereof. 
   
   
       3 . The garlic supplement according to  claim 1  wherein the garlic is in a form selected from the group consisting of fresh garlic, dry powder, oils, macerates, extracts, aged extracts, steam distilled oils and mixtures thereof. 
   
   
       4 . The garlic supplement according to  claim 3  wherein the garlic is in the form of a dry powder. 
   
   
       5 . The garlic supplement according to  claim 1  wherein the core(s) further comprise(s) one or more carriers selected from the group consisting of binders, fillers, deodorizers and other pharmaceutically acceptable excipients. 
   
   
       6 . The garlic supplement according to  claim 5  wherein the core further comprises a deodorizer. 
   
   
       7 . The garlic supplement according to  claim 1  wherein the enteric coating is selected from the group consisting cellulose, methylcellulose, natural polymers, synthetic polymers, cross-linked gelatin and mixtures thereof. 
   
   
       8 . The garlic supplement according to  claim 7  wherein the enteric coating is selected from cellulose or methylcellulose or mixtures thereof. 
   
   
       9 . The garlic supplement according to  claim 1  wherein the thickness of the enteric-coating is not greater than about 0.5 mm. 
   
   
       10 . The garlic supplement according to  claim 1  wherein the deodorizer is present in an amount from about 0.5 to about 1.0 weight % of the total weight of the garlic supplement. 
   
   
       11 . The garlic supplement according to  claim 10  wherein the deodorizer is present in an amount from about 0.6 weight % of the total weight of the garlic supplement. 
   
   
       12 . The garlic supplement according to  claim 1  which further comprises an external coating applied over the enteric coating. 
   
   
       13 . The garlic supplement according to  claim 12  wherein the deodorizer is incorporated in the external coating. 
   
   
       14 . The garlic supplement according to  claim 12  wherein the external coating has a thickness in the range of from 0.001 mm to 1.500 mm. 
   
   
       15 . The garlic supplement according to  claim 12  wherein the external coating comprises one or more coating agents selected from the group consisting of microcrystalline waxes, carnauba wax, polyvinylpyrroldidone, sugars and mixtures thereof. 
   
   
       16 . The garlic supplement according to  claim 1  wherein the garlic supplement is in a form selected from the group consisting of a tablet cross-linked capsule, gelatin capsule, suspensions, emulsions, enteral feeds, functional foods or micro-particles. 
   
   
       17 . The garlic supplement according to  claim 16  wherein the core(s) is in a form selected from the group consisting of liquids, solids, fluids, gels and mixtures thereof. 
   
   
       18 . A garlic supplement comprising:
 (a) one or more cores comprising garlic; and   (b) an enteric coating encasing the core(s) which is insoluble at pH less than about 5 but soluble at a pH greater than about 5; and   (c) an external coating over the enteric coating wherein the external coating comprises a deodorizer.   
   
   
       19 . The garlic supplement according to  claim 18  wherein the enteric coating further comprises a deodorizer. 
   
   
       20 . The garlic supplement according to  claim 18  wherein the deodorizer is selected from the group consisting of extracts, aqueous extracts, natural flavours or oils derived from parsley seed, Lamiaceae plants, green tea, and flavanoid containing plants or synthetic versions thereof and mixtures thereof.