US2008311131A1PendingUtilityA1
Human Mob-5 (IL-24) receptors and uses thereof
Est. expiryAug 29, 2021(expired)· nominal 20-yr term from priority
Inventors:Peng Liang
C07K 14/54A61P 35/00C07K 14/7155G01N 33/5011C07K 16/244G01N 2333/715G01N 33/5753G01N 33/575G01N 33/57535
61
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Claims
Abstract
The present invention provides the receptors for Mob-5 (IL-24). One of the Mob-5 receptors comprises IL-22R1 and IL-20R2. Another Mob-5 receptor comprises IL-20R1 and IL-22R2. The invention also provides methods of inhibiting the Mob-5 receptor as well as methods of detecting cancer by detecting the presence of the Mob-5 receptor.
Claims
exact text as granted — not AI-modified1 - 11 . (canceled)
12 . A method for inhibiting mob-5 induced cellular transformation phenotype comprising inhibiting the Mob-5 receptor in a cell so as to inhibit the expression of the mob-5 induced cellular transformation phenotype, wherein the Mob-5 receptor is a IL-22R1/IL-20R2 heterodimer.
13 - 14 . (canceled)
15 . The method of claim 12 , wherein the Mob-5 receptor is inhibited by an antibody to the Mob-5 receptor.
16 - 20 . (canceled)
21 . A method for inhibiting cancer comprising inhibiting the Mob-5 in a cell so as to inhibit Mob-5 induced cancer, wherein the Mob-5 receptor is a IL-22R1/IL-20R2 heterodimer.
22 - 23 . (canceled)
24 . The method of claim 21 , wherein the Mob-5 receptor is inhibited by an antibody to the Mob-5 receptor.
25 - 48 . (canceled)Join the waitlist — get patent alerts
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