Smoking articles and method for incorporating salts of lanthanide metals for reducing TPM cytotoxicity and targeted constituents in tobacco smoke

Abstract

Provided is a smoking article and method for reducing TPM cytotoxicity and targeted constituents in mainstream smoke. The smoking article includes tobacco material including a salt of a lanthanide metal. The method includes combining a salt of a lanthanide metal, water, and optionally glycerin to produce a solution that is applied to tobacco material. Preferably, the salt is an acetate, a sulfate, or a gluconate.

1 . A smoking article comprising:
 a portion of tobacco material including a salt of a lanthanide metal wherein said salt is an acetate, a sulfate, or a gluconate.   
   
   
       2 . The smoking article of  claim 1 , wherein said portion of tobacco material further includes glycerin. 
   
   
       3 . The smoking article of  claim 2 , wherein glycerin is included in said smoking article in an amount of about 2% to about 25%. 
   
   
       4 . The smoking article of  claim 2 , wherein glycerin is included in said smoking article in an amount of about 5% to about 15%. 
   
   
       5 . The smoking article of  claim 1 , wherein said acetate salt of a lanthanide is selected from the group consisting of La(OAc) 3 .xH 2 O, Ce(OAc) 3 .H 2 O, Eu(OAc) 3 .H 2 O, Lu(OAc) 3 .H 2 O, and combinations thereof. 
   
   
       6 . The smoking article of  claim 1 , wherein said smoking article includes said salt of a lanthanide metal in an amount of about 0.25% to about 25% by weight of the salt of a lanthanide metal. 
   
   
       7 . The smoking article of  claim 1 , further including (a) humectants; (b) sweeteners; and/or (c) flavorants. 
   
   
       8 . A method of treating tobacco smoke produced by the smoking article of  claim 1 , wherein the salt of the lanthanide reduces cytotoxicity of the tobacco smoke by about 1% to about 60%. 
   
   
       9 . A method of treating tobacco smoke produced by the smoking article of  claim 2 , wherein salt of the lanthanide and glycerin reduces the cytotoxicity and mutagenicity of tobacco smoke produced by said smoking article by about 20% to about 70%. 
   
   
       10 . A method of treating tobacco smoke produced by the smoking article of  claim 1 , wherein the salt of the lanthanide reduces the mutagenicity of said mainstream smoke by about 1% to about 50%. 
   
   
       11 . A method of treating tobacco smoke produced by the smoking article of  claim 1 , wherein the salt of the lanthanide metal reduces the presence of catechol, hydroquinone, resorcinol, and naphthalene by about 1% to about 80%. 
   
   
       12 . A method of making a smoking article for reducing TPM cytotoxicity and mutagenicity in smoke comprising:
 contacting a portion of tobacco material with a solution containing a salt of a lanthanide metal to form a treated portion of tobacco material; and   incorporating said treated portion of tobacco material into a smoking article,   
     wherein said salt of a lanthanide metal is an acetate, a sulfate, or a gluconate. 
   
   
       13 . The method of  claim 12 , wherein said solution further includes glycerin. 
   
   
       14 . The method of  claim 13 , wherein said glycerin is included in said solution in an amount of about 2% to about 25%. 
   
   
       15 . The method of  claim 13 , wherein said glycerin is included in said solution in an amount of about 5% to about 15%. 
   
   
       16 . The method of  claim 12 , further including drying said treated portion of tobacco material. 
   
   
       17 . The method of  claim 12 , wherein said salt of a lanthanide metal is sprayed onto said portion of tobacco material, added drop wise to said portion of tobacco material, and/or said portion of tobacco material is placed in a tumbling device prior to contacting said portion of tobacco material with said solution. 
   
   
       18 . The method of  claim 12 , wherein said treated portion of tobacco material includes said salt of a lanthanide metal in an amount of about 0.25% to about 25% by weight of said salt of a lanthanide metal. 
   
   
       19 . The method  claim 13 , wherein (i) when said portion of tobacco material is treated with said solution containing glycerin and a salt of a lanthanide metal, the cytotoxicity and mutagenicity is reduced by about 20% to about 70%, (ii) said smoking article produces a mainstream smoke having a cytotoxicity that is reduced by about 1% to about 60% when said tobacco material is treated with said solution including a salt of a lanthanide metal, (iii) the mutagenicity of said mainstream smoke is reduced by about 1% to about 50% when said tobacco material is treated with a salt of a lanthanide metal, and/or (iv) said mainstream smoke has a reduced presence of catechol, hydroquinone, resorcinol, and naphthalene by about 1% to about 80%. 
   
   
       20 . The method of  claim 12 , wherein said lanthanide metal is selected from the group consisting of lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, and combinations thereof.