US2009011424A1PendingUtilityA1

Cancer-suppressing agents

Assignee: UNIV TOKYO MEDICAL & DENTALPriority: Oct 25, 2005Filed: Jul 23, 2008Published: Jan 8, 2009

Est. expiryOct 25, 2025(expired)· nominal 20-yr term from priority

Inventors:Akiko Misawa Jun Inoue Issei Imoto Johji Inazawa

A61P 35/00G01N 33/57557C12Q 2600/118C12Q 2600/136C12Q 1/6886C12Q 2600/154C12Q 2600/112C07K 14/70567

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Claims

Abstract

It is an object of the present invention to provide a cancer-suppressing agent comprising a novel cancer-suppressing gene based on the discovery of such cancer-suppressing gene. The present invention provides a cancer-suppressing agent which comprises NR1I2 gene or a homologous gene thereof; and a cancer-suppressing agent which comprises NR1I2 protein or a homologous protein thereof.

Claims

exact text as granted — not AI-modified

1 . A method for detecting and diagnosing cancer, which comprises a step of analyzing NR1I2 gene in a test sample using DNA or RNA containing NR1I2 gene in its entirety or a part thereof. 
     
     
         2 . The method of  claim 1 , wherein the analysis involves detection of mutation of the gene or detection of abnormal expression level of the gene. 
     
     
         3 . The method of  claim 1 , which is a method for screening for cancer to which the cancer-suppressing agent of  claim 1  can be applied.

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