Large dose ribavrin formulatons

Abstract

The present invention is related to pharmaceutical dosage forms of ribavirin which are designed to increase patient compliance to a ribavirin therapy. Examples of such dosage forms include 400 mg to 600 mg tablets. These dosage forms are bioequivalent to multiple doses of tablets containing small amounts of ribavirin.

1 . A daily dosage regimen of ribavirin treatment comprising administering to a patient in need thereof exactly one dosage form of ribavirin and 8 hours to 16 hours later administering another one dosage form of ribavirin. 
     
     
         2 . The daily dosage regimen of  claim 1 , wherein the dosage form comprises 400 mg to 600 mg of ribavirin. 
     
     
         3 . The daily dosage regimen of  claim 2 , wherein the dosage form is a tablet which comprises 400 mg of ribavirin. 
     
     
         4 . The daily dosage regimen of  claim 3 , wherein the dosage form is a tablet which comprises 600 mg of ribavirin.