Carrier Polymer Particle, Process for Producing the Same, Magnetic Particle for Specific Trapping, and Process for Producing the Same

Abstract

Carrier polymer particles comprising organic polymer particles having a particle diameter of 0.1 to 20 micrometers and a saccharide with which the surface of the organic polymer particles is covered, the organic polymer particles and the saccharide being chemically bonded.

1 . Carrier polymer particles comprising:
 organic polymer particles having a particle diameter of 0.1 to 20 micrometers and   a saccharide with which the surface of the organic polymer particles is covered,   the organic polymer particles and the saccharide being chemically bonded.   
   
   
       2 . The carrier polymer particles according to  claim 1 ,
 wherein the saccharide is a polysaccharide.   
   
   
       3 . The carrier polymer particles according to  claim 1 ,
 wherein the saccharide is carboxymethylated.   
   
   
       4 . The carrier polymer particles according to  claim 1 ,
 wherein the organic polymer particles and the saccharide being chemically bonded by a bonding group including at least one of an amide bond and an ester bond.   
   
   
       5 . A process for producing carrier polymer particles comprising covering the surface of organic polymer particles having a particle diameter of 0.1 to 20 micrometers with a saccharide by chemically bonding the organic polymers and the saccharide. 
   
   
       6 . The process according to  claim 5 ,
 wherein when chemically bonding, the organic polymer particles have a first functional group and the saccharide has a second functional group, and   the organic polymer particles and the saccharide are chemically bonded by reacting the first functional group and the second functional group.   
   
   
       7 . The process according to  claim 5 ,
 wherein the first functional group is at least one functional group selected from the group consisting of a carboxyl group, an epoxy group, an amino group, and a tosyl group.   
   
   
       8 . A process for producing carrier polymer particles comprising:
 covering organic polymer particles with a particle diameter of 0.1 to 20 micrometers, which has a functional group having reactivity with a carboxyl group, with a saccharide having a carboxyl group by chemically bonding the organic polymer particles and the saccharide, and   treating the organic polymer particles, of which the surface has been covered with the saccharide, with a basic solution.   
   
   
       9 . The process according to  claim 8 ,
 wherein the saccharide is a polysaccharide.   
   
   
       10 . The process according to  claim 8 ,
 wherein the chemical bonding is achieved by a bonding group including at least one of an amide bond or an ester bond.   
   
   
       11 . The process according to  claim 8 ,
 wherein the functional group having reactivity with the carboxyl group is at least one functional group selected from the group consisting of an amino group, a hydroxyl group, and an epoxy group.   
   
   
       12 . The process according to  claim 8 ,
 further comprising chemically bonding a probe for specifically trapping a target material to the saccharide.   
   
   
       13 . Magnetic particles for specific trapping comprising:
 magnetic particles having a particle diameter of 0.1 to 20 micrometers and a saccharide, the magnetic particles and the saccharide being chemically bonded, and   a probe for specifically trapping a target material being bonded to the saccharide.   
   
   
       14 . The magnetic particles for specific trapping according to  claim 13 ,
 wherein the saccharide is a polysaccharide.   
   
   
       15 . The magnetic particles for specific trapping according to  claim 13 ,
 wherein the saccharide is carboxymethylated.   
   
   
       16 . The magnetic particles for specific trapping according to  claim 13 ,
 wherein the magnetic particles and the saccharide being chemically bonded by a bonding group include at least one of an amide bond and an ester bond.   
   
   
       17 . The magnetic particles for specific trapping according to  claim 13 ,
 wherein the magnetic particles are obtained by polymerization of a polymer layer on a magnetic material layer of mother particles, the mother particles comprising nuclear particles and the magnetic material layer formed on the surface of the nuclear particles, and   the magnetic material layer comprises at least one of Fe 2 O 3  and Fe 3 O 4 .   
   
   
       18 . The magnetic particles for specific trapping according to  claim 13 ,
 wherein the probe is at least one probe selected from proteins, peptides, nucleic acids, glycoside compounds, and synthetic chemical materials.   
   
   
       19 . A process for producing the magnetic particles for specific trapping comprising:
 chemically bonding magnetic particles having a diameter of 0.1 to 20 micrometers to a saccharide and   chemically bonding a probe for specifically trapping the target material to a saccharide.   
   
   
       20 . The process according to  claim 19 ,
 wherein when chemically bonding the magnetic particles and the saccharide, the magnetic particles have a first functional group and the saccharide has a second functional group, and the magnetic particles and the saccharide are chemically bonded by reacting the first functional group and the second functional group.   
   
   
       21 . The process according to  claim 19 ,
 wherein the first functional group is at least one functional group selected from the group consisting of a carboxyl group, an epoxy group, an amino group, and a tosyl group.