Cosmetic or dermatological preparations comprising oligopeptides for lightening the skin of age marks and/or for preventing tanning of the skin, in particular tanning of the skin caused by uv radiation

Abstract

Cosmetic or pharmaceutical preparations which are distinguished by an effective content of one or more monomeric or homo- or heterodimeric or homo- or heterotrimeric or homo- or heterotetrameric oligopeptides, where these oligopeptides are based on a Structure Val-Val-Arg-Pro SEQ ID NO: 1 as homo- or heteromonomer.

1 . A cosmetic or dermatological topical water-in-oil preparation for cosmetic and topical dermatological lightening of the skin or preventing tanning of the skin caused by UV radiation which comprises of one or more monomeric oligopeptides selected from the group consisting of: 
       
         
           
           
               
               
           
         
       
       wherein:
 R represents a branched or unbranched, saturated or unsaturated alkyl radical having C 1 -C 30  carbon atoms, 
 R′ and R″ independently of one another may be selected from the group consisting of hydrogen and branched or unbranched, saturated of unsaturated alkyl radical having C 1 -C 30  carbon atoms, 
 
       one or more cosmetically or dermatologically acceptable active ingredients, auxiliaries and/or additives; and 
       a cosmetically or dermatologically acceptable carrier. 
     
     
         2 . The topical water-in-oil preparation of  claim 1 , wherein the oligopeptides(s) is/are present in cosmetic or dermatological topical preparations in concentration of 0.000001-10% by weight, based on the total weight of the preparations. 
     
     
         3 . The topical water-in-oil preparation of  claim 2 , wherein the oligopeptides(s) is/are present in the cosmetic or dermatological topical preparations in concentrations of 0.0001-1% by weight based on the total weight of the preparations. 
     
     
         4 . The topical water-in-oil preparation of  claim 3 , wherein the oligopeptides(s) is/are present in the cosmetic or dermatological topical preparations in concentrations of 0.0001-0.1% by weight based on the total weight of the preparations. 
     
     
         5 . The cosmetic or dermatological topical water-in-oil preparation of  claim 1  wherein the oligopeptide is 
       
         
           
           
               
               
           
         
       
     
     
         6 . The cosmetic or dermatological topical water-in-oil preparation of  claim 1  wherein the oligopeptide is 
       
         
           
           
               
               
           
         
       
     
     
         7 . The cosmetic or dermatological topical water-in-oil preparation of  claim 1  wherein the oligopeptide is 
       
         
           
           
               
               
           
         
       
     
     
         8 . The cosmetic or dermatological topical water-in-oil preparation of  claim 1  wherein the oligopeptide is 
       
         
           
           
               
               
           
         
       
     
     
         9 . The cosmetic or dermatological topical water-in-oil preparation of  claim 6  wherein R′ and R″ is hydrogen. 
     
     
         10 . The cosmetic or dermatological topical water-in-oil preparation of  claim 7  wherein R is methyl. 
     
     
         11 . The cosmetic or dermatological topical water-in-oil preparation of  claim 7  wherein R is an n-C 15  or n-C 17  alkyl radical. 
     
     
         12 . The cosmetic of dermatological topical water-in-oil preparation of  claim 8  wherein R is methyl, R′ is hydrogen and R″ is hydrogen.