US2009023717A1PendingUtilityA1

Morphine-bridged indazole derivatives

Assignee: FEURER ACHIMPriority: Sep 26, 2002Filed: Sep 18, 2008Published: Jan 22, 2009
Est. expirySep 26, 2022(expired)· nominal 20-yr term from priority
A61P 43/00A61P 25/28A61P 25/00C07D 471/04
58
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Claims

Abstract

The present invention relates to novel morpholine-bridged indazole derivatives which stimulate soluble guanylate cyclase, to process for the preparation thereof, and to the use thereof for producing medicaments, in particular medicaments for the treatment of disorders of the central nervous system.

Claims

exact text as granted — not AI-modified
1 . A method for the treatment of central nervous system diseases comprising administering to a human or animal an effective amount of a compound of of the formula 
     
       
         
         
             
             
         
       
       in which 
       R 1  is 
     
     
       
         
         
             
             
         
       
       
         where 
         n is 1 or 2, and 
       
       R 2  is hydrogen or NH 2 , 
     
     or a salt, solvate, or solvate of a salt thereof. 
   
   
       2 . A method for the treatment of disorders of perception, concentration, learning or memory comprising administering to a human or animal an effective amount of a compound of the formula 
     
       
         
         
             
             
         
       
       in which 
       R 1  is 
     
     
       
         
         
             
             
         
       
       
         where 
         n is 1 or 2, and 
       
       R 2  is hydrogen or NH 2 , 
     
     or a salt, solvate, or solvate of a salt thereof.

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