US2009048348A1PendingUtilityA1

Method for treating autism

Assignee: FOREST LAB HOLDINGS LTDPriority: Apr 5, 2004Filed: Oct 17, 2008Published: Feb 19, 2009
Est. expiryApr 5, 2024(expired)· nominal 20-yr term from priority
Inventors:Michael Chez
A61K 31/135A61P 25/00A61K 31/00
66
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

A method for treating autism comprising the step of administering an effective amount of a medicament characterized as a NMDA-receptor antagonist or a pharmaceutically acceptable salt thereof.

Claims

exact text as granted — not AI-modified
1 . A method for treating autism, comprising the step of:
 administering an effective amount of a medicament characterized as a NMDA-receptor antagonist or a pharmaceutically acceptable salt thereof.   
   
   
       2 . The method according to  claim 1 , wherein the step of administering an effective amount of medicament includes the step of administering the medicament in a concentration ranging from approximately 1 mg to approximately 100 mg per day. 
   
   
       3 . The method according to  claim 1 , wherein the step of administering an effective amount of medicament includes the step of administering the medicament in a concentration ranging from approximately 5 mg to approximately 20 mg per day. 
   
   
       4 . The method according to  claim 1 , wherein the step of administering an effective amount of a medicament includes the step of administering an effective amount of a medicament represented by the following chemical structure: 
     
       
         
         
             
             
         
       
     
     wherein X 1  comprises CH 2  or R 15 ; wherein R 1-15  are the same or different and comprise H, an amino group, a primary amine, a secondary amine, a tertiary amine, a quaternary ammonium group, a hydroxy group, a straight or branched alkyl, cycloalkyl, polycycloalkyl, heterocycloalkyl, aryl, alkaryl, aralkyl, alkoxy, alkenyl, alkynyl group containing approximately 1 to approximately 50 carbon atom(s), a silyl or siloxyl group containing approximately 1 to approximately 50 silicon atom(s), and combinations thereof. 
   
   
       5 . The method according to  claim 4 , wherein the step of administering an effective amount of medicament includes the step of administering the medicament in a concentration ranging from approximately 1 mg to approximately 100 mg per day. 
   
   
       6 . The method according to  claim 4 , wherein the step of administering an effective amount of medicament includes the step of administering the medicament in a concentration ranging from approximately 5 mg to approximately 20 mg per day. 
   
   
       7 . The method according to  claim 1 , wherein the step of administering an effective amount of a medicament includes the step of administering an effective amount of a medicament represented by the following chemical structure: 
     
       
         
         
             
             
         
       
     
     wherein R 1-3  are the same or different and comprise H, an amino group, a primary amine, a secondary amine, a tertiary amine, a quaternary ammonium group, a hydroxy group, a straight or branched alkyl, cycloalkyl, polycycloalkyl, heterocycloalkyl, aryl, alkaryl, aralkyl, alkoxy, alkenyl, alkynyl group containing approximately 1 to approximately 50 carbon atom(s), a silyl or siloxyl group containing approximately 1 to approximately 50 silicon atom(s), and combinations thereof. 
   
   
       8 . The method according to  claim 7 , wherein the step of administering an effective amount of medicament includes the step of administering the medicament in a concentration ranging from approximately 1 mg to approximately 100 mg per day. 
   
   
       9 . The method according to  claim 7 , wherein the step of administering an effective amount of medicament includes the step of administering the medicament in a concentration ranging from approximately 5 mg to approximately 20 mg per day. 
   
   
       10 . The method according to  claim 1 , wherein the step of administering an effective amount of a medicament includes the step of administering an effective amount of a medicament represented by the following chemical structure: 
     
       
         
         
             
             
         
       
     
   
   
       11 . The method according to  claim 10 , wherein the step of administering an effective amount of medicament includes the step of administering the medicament in a concentration ranging from approximately 1 mg to approximately 100 mg per day. 
   
   
       12 . The method according to  claim 10 , wherein the step of administering an effective amount of medicament includes the step of administering the medicament in a concentration ranging from approximately 5 mg to approximately 20 mg per day. 
   
   
       13 . The method according to  claim 1 , wherein the step of administering an effective amount of a medicament includes the step of administering an effective amount of a medicament represented by the following chemical structure: 
     
       
         
         
             
             
         
       
     
   
   
       14 . The method according to  claim 13 , wherein the step of administering an effective amount of medicament includes the step of administering the medicament in a concentration ranging from approximately 1 mg to approximately 100 mg per day. 
   
   
       15 . The method according to  claim 13 , wherein the step of administering an effective amount of medicament includes the step of administering the medicament in a concentration ranging from approximately 5 mg to approximately 20 mg per day. 
   
   
       16 . The method according to  claim 1 , wherein the step of administering an effective amount of a medicament includes the step of administering an effective amount of 1-amino-3,5-dimethyladamantane hydrochloride and pharmaceutically acceptable derivatives thereof. 
   
   
       17 . The method according to  claim 16 , wherein the step of administering an effective amount of medicament includes the step of administering the medicament in a concentration ranging from approximately 1 mg to approximately 100 mg per day. 
   
   
       18 . The method according to  claim 16 , wherein the step of administering an effective amount of medicament includes the step of administering the medicament in a concentration ranging from approximately 5 mg to approximately 20 mg per day. 
   
   
       19 . A method for treating autism, comprising the step of:
 administering an effective amount of a medicament represented by the following chemical structure:   
     
       
         
         
             
             
         
       
       wherein X 1  comprises CH 2  or R 15 ; wherein R 1-15  are the same or different and comprise H, an amino group, a primary amine, a secondary amine, a tertiary amine, a quaternary ammonium group, a hydroxy group, a straight or branched alkyl, cycloalkyl, polycycloalkyl, heterocycloalkyl, aryl, alkaryl, aralkyl, alkoxy, alkenyl, alkynyl group containing approximately 1 to approximately 50 carbon atom(s), a silyl or siloxyl group containing approximately 1 to approximately 50 silicon atom(s), and combinations thereof; and 
       wherein the step of administering the medicament includes the step of administering the medicament in a concentration ranging from approximately 5 mg to approximately 20 mg per day. 
     
   
   
       20 . A method for treating autism, comprising the step of:
 administering an effective amount of a medicament characterized as a NMDA-receptor antagonist or a pharmaceutically acceptable salt thereof;   wherein the step of administering an effective amount of a medicament includes the step of administering an effective amount of 1-amino-3,5-dimethyladamantane hydrochloride and pharmaceutically acceptable derivatives thereof; and   wherein the step of administering an effective amount of medicament includes the step of administering the medicament in a concentration ranging from approximately 5 mg to approximately 20 mg per day.

Join the waitlist — get patent alerts

Track US2009048348A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.