Methods for attaining enhanced sexual wellness using anhydrous compositions

Abstract

The invention relates to a method of attaining enhanced sexual wellness of an individual comprising administering to the genital areas of the individual, an anhydrous composition comprising a vasodilator, for example, a niacin derivative, and an acceptable carrier. The method according to the invention does not cause flushing.

1 . A method of attaining enhanced sexual wellness of an individual comprising administering to the genital areas of said individual, an anhydrous composition comprising an effective amount of a niacin derivative and an acceptable carrier. 
   
   
       2 . A method of  claim 1 , wherein said composition is administered between 5 minutes to 30 minutes prior to intercourse. 
   
   
       3 . A method according to  claim 1 , wherein said niacin derivative is selected from nicotinic acid, methyl niconate, methyl nicotinate, benzyl nicotinate, nicotinamide, and niacinamide. 
   
   
       4 . A method according to  claim 1 , wherein said niacin derivative is present in an amount of from about 0.1 to about 0.5% by weight. 
   
   
       5 . A method according to  claim 1 , wherein said carrier is a polyhydric alcohol. 
   
   
       6 . A method according to  claim 5 , wherein said polyhydric alcohol is selected from polyethylene glycol, propylene glycol, hexalene glycol, butylenes glycol and mixtures thereof. 
   
   
       7 . A method according to  claim 5  wherein said polyhydric alcohol is a mixture of polyethylene glycol and propylene glycol. 
   
   
       8 . A method according to  claim 7 , wherein the weight ratio of polyethylene glycol to propylene glycol in said mixture is about 3:1. 
   
   
       9 . A method according to  claim 1 , wherein said composition comprises an antioxidant in an amount effective to prevent the degradation of said polyhydric alcohols. 
   
   
       10 . A method according to  claim 9 , wherein said antioxidant is selected from the group consisting of tocopherol, ascorbic acid and butylated hydroxytoluene (BHT), wherein said polyhydric alcohol is selected from the group consisting of propylene glycol, polyethylene glycol, butylethylene glycol, hexalene glycol and combinations thereof. 
   
   
       11 . A method according to  claim 10 , wherein said antioxidant is present in an amount of from about 0.05% to about 3%. 
   
   
       12 . A method according to  claim 10 , wherein said antioxidant is selected from α-tochopherol, α-tochopherol acetate, and mixtures thereof. 
   
   
       13 . A method according to  claim 1 , wherein said composition comprises an effective amount of at least one sensitivity enhancer. 
   
   
       14 . A method according to  claim 13 , wherein said sensitivity enhancer is present in an amount ranging from about 0.05 to about 5% by weight. 
   
   
       15 . A method according to  claim 14 , wherein said sensitivity enhancer is selected from a cooling compound, a warming compound, a tingling compound, and mixtures thereof. 
   
   
       16 . A method according to  claim 15 , wherein said cooling compound is selected from 2-Isopropyl-N, 2,3-trimethylbutyramide, N-Ethyl-p-menthane-3-carboxamide and Ethyl 3-(p-menthane-3-carboxamido) acetate Menthone glycerol ketal, (−)-Menthyl lactate, (−)-Isopulegol, Alpha Glucosyl Hisperidin and mixtures thereof. 
   
   
       17 . A method according to  claim 15 , wherein said warming compound is selected from piperine, 1-Acetoxychavicol Acetate, α-hydroxyshansool, Timurol, Hesperidin, ginger extract, and mixtures thereof. 
   
   
       18 . A method according to  claim 15 , wherein said tingling compound is selected from Shansools, Spilanthol, Timurol and mixtures thereof. 
   
   
       19 . A method according to  claim 1 , further comprising at least one of menthyl salicylate and menthyl lactate. 
   
   
       20 . A method according to  claim 1 , wherein said composition comprises an effective amount of a lubricating agent. 
   
   
       21 . A method according to  claim 20 , wherein said lubricating agent is selected from the group consisting of carboxymethylcellulose, hydroxyethylcellulose, hydroxypropyl methylcellulose, hydroxypropylcellulose, and mixtures thereof. 
   
   
       22 . A method according to  claim 21 , wherein said lubricating agent is present in an amount of from about 0.05 to about 5% by weight. 
   
   
       23 . A method according to  claim 1 , wherein said composition is non-flushing and wherein said increase in blood flow is less than a 300% increase.