Composition For Treatment of Articular Cartilage Damage

Abstract

Disclosed is a composition for the treatment of cartilage or bone damage or loss or defect. The composition comprises mesenchymal stem cells separated from umbilical cord blood and/or mesenchymal stem cells proliferated and/or differentiated. The composition also comprise chondrocytes and/or chondroblasts, or osteocytes and/or osteoblasts, differentiated from the mesenchymal stem cells separated from the umbilical cord blood.

1 - 14 . (canceled) 
   
   
       15 . A composition comprising mesenchymal stem cells isolated from umbilical cord blood. 
   
   
       16 . The composition according to  claim 15 , wherein the mesenchymal stem cells are further proliferated. 
   
   
       17 . The composition according to  claim 15 , which treats cartilage damage, loss, or defects when administered to a site of cartilage damage, loss, or defects in a subject. 
   
   
       18 . The composition according to  claim 15 , which treats bony damage, loss, or defects when administered to a site of bony damage, loss, or defects in a subject. 
   
   
       19 . The composition according to  claim 15 , which avoids or minimizes immune reactions when administered in a subject. 
   
   
       20 . The composition of  claim 19 , wherein said immune reaction is rejection reaction. 
   
   
       21 . The composition according to  claim 15 , which is in an injectable formulation. 
   
   
       22 . The composition according to  claim 15 , wherein said composition contains 1×10 6  to 5×10 7  cells per mL of the composition.