External Preparation for Athlete's Foot Treatment

Abstract

External preparations for athlete's foot treatment capable of enhancing patient's compliance and capable of reducing the symptom of rubefaction, comprising an anti-trichophyton drug mixed with at least one compound selected from among 1-menthol, menthol analogue compounds and bactericidal compounds.

1 . An external preparation for athlete's foot treatment, comprising an anti-trichophyton drug mixed with 3-1-menthoxypropane-1,2-diol. 
   
   
       2 . The external preparation for athlete's foot treatment of  claim 1 , wherein the anti-trichophyton drug and 3-1-menthoxypropane-1,2-diol are blended in 0.1-10% by mass and 0.5-5% by mass respectively. 
   
   
       3 . The external preparation for athlete's foot treatment of  claim 1 , wherein the anti-trichophyton drug is selected from benzylamine type, allylamine type, thiocarbamic acid type and imidazole type antifungal agents. 
   
   
       4 . The external preparation for athlete's foot treatment of  claim 1 , wherein the anti-trichophyton drug is one kind selected from butenafine hydrochloride, terbinafine hydrochloride, tolnaftate, bifonazole, ketoconazole, neticonazole hydrochloride and lanoconazole. 
   
   
       5 . The external preparation for athlete's foot treatment of  claim 4  wherein butenafine hydrochloride and 3-1-menthoxypropane-1,2-diol are blended. 
   
   
       6 . The external preparation for athlete's foot treatment of  claim 1  further comprising at least one kind of a local anesthetic, an antihistamine and an anti-inflammatory drug. 
   
   
       7 . The external preparation for athlete's foot treatment of  claim 6 , wherein the local anesthetic is dibucaine hydrochloride, or lidocaine or its salt. 
   
   
       8 . The external preparation for athlete's foot treatment of  claim 6 , wherein the antihistamine is chlorpheniramine maleate, or diphenhydramine or its salt. 
   
   
       9 . The external preparation for athlete's foot treatment of  claim 6 , wherein the anti-inflammatory drug is glycyrrhetinic acid or its salt, or allantoin. 
   
   
       10 . The external preparation for athlete's foot treatment of  claim 6  wherein butenafine hydrochloride, 3-1-menthoxypropane-1,2-diol, dibucaine hydrochloride, chlorpheniramine maleate and glycyrrhetinic acid are blended.