US2009099339A1PendingUtilityA1

Antibody and antibody fragments for inhibiting the growth of tumors

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Assignee: IMCLONE SYSTEMS INCPriority: Jun 7, 1995Filed: Jul 9, 2008Published: Apr 16, 2009
Est. expiryJun 7, 2015(expired)· nominal 20-yr term from priority
Inventors:Neil I. GoldsteinNicholas A. GiorgioSteven JonesJose Saldanha
C07K 2317/24C07K 16/2863C07K 2317/73A61K 2039/505C07K 2319/00A61K 38/00
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Claims

Abstract

Chimerized and humanized versions of anti EGF receptor antibody 225 and fragments thereof for treatment of tumors.

Claims

exact text as granted — not AI-modified
1 .- 91 . (canceled) 
     
     
         92 . An antibody which is c225. 
     
     
         93 . The antibody of  claim 92 , which is conjugated to a cytotoxic agent. 
     
     
         94 . The antibody of  claim 93 , wherein said cytotoxic agent is doxorubicin. 
     
     
         95 . The antibody of  claim 93 , wherein said cytotoxic agent is taxol. 
     
     
         96 . The antibody of  claim 93 , wherein said cytotoxic agent is cisplatin.

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