US2009124658A1PendingUtilityA1

Treatments for Viral Infections

56
Individually held — no corporate assignee on recordPriority: Aug 23, 1999Filed: Dec 11, 2008Published: May 14, 2009
Est. expiryAug 23, 2019(expired)· nominal 20-yr term from priority
Inventors:Robert H. Keller
A61P 31/16A61P 31/12A61P 31/18A61P 31/14A61K 31/714A61K 31/525A61K 31/7048A61K 31/4415A61K 31/51A61K 31/47A61K 31/455A61K 31/277A61K 31/4704A61K 31/4015A61K 31/4166A61K 45/06A61K 31/4706
56
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Claims

Abstract

The present invention relates to improved methods and compositions for treating viral infections and other diseases and conditions that induce a cytokine storm. More particularly, the present invention relates to novel compositions comprising quercitin, and an anti-convulsant, such as phenyloin, in combination with multivitamins as an anti-viral composition and methods of use thereof.

Claims

exact text as granted — not AI-modified
1 . A method of reducing the activity of a single stranded RNA virus in a virus-infected cell or a virus-infected subject, comprising administering to the cell or subject a therapeutically effective amount of a composition comprising quercetin or a derivative thereof, at least one calcium channel blocker component, an anticonvulsant component, a quinoline or a derivative thereof, and a multivitamin component, in sufficient amounts to treat and reduce viral activity in the cell or subject. 
   
   
       2 . The method according to  claim 1 , wherein the single stranded RNA virus is selected from the group comprising HIV and an avian influenza virus. 
   
   
       3 . The method according to  claim 2  wherein the avian influenza virus is an H5N1 of avian influenza virus. 
   
   
       4 . A method of reducing a pro-inflammatory response and/or cytokine storm in a cell or in a subject, comprising administering to the cell or subject a therapeutically effective amount of a composition comprising quercetin or a derivative thereof, at least one calcium channel blocker component, an anticonvulsant component, a quinoline or a derivative thereof, and a multivitamin component, in sufficient amounts to treat and reduce the pro-inflammatory response and/or cytokine storm in the cell or subject. 
   
   
       5 . The method according to  claim 4  wherein the pro-inflammatory response and/or cytokine storm is the result of an infection of the cell or subject with a pathogenic agent. 
   
   
       6 . The method according to  claim 5  wherein the pathogenic agent is a virus. 
   
   
       7 . The method according to  claim 6  wherein the virus is an avian influenza virus. 
   
   
       8 . The method according to  claim 7  wherein the avian influenza virus is the H5N1 avian influenza virus.

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