US2009124699A1PendingUtilityA1

Silicone Material for Releasing an Active Molecule

Assignee: BLUESTAR SILICONES FRANCEPriority: Dec 24, 2004Filed: Dec 23, 2005Published: May 14, 2009
Est. expiryDec 24, 2024(expired)· nominal 20-yr term from priority
A61K 8/895A61K 2800/56A61P 17/00A61K 8/375A61Q 19/00A61K 8/37A61K 8/0208A61K 8/34A61K 8/89
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Claims

Abstract

The invention concerns a material, preferably adhesive, for releasing an active molecule for cosmetic use or personal care or a pharmaceutically or biologically active molecule for pharmaceutical use, which is formed of a silicone substance, preferably adhesive, wherein is incorporated said molecule and a compatibility agent wherein said active molecule is soluble, said compatibility agent being selected among isopropyl myristate, isopropyl palmitate, isononyl isononanoate, neopentyl glycol dioctanoate, branched paraffins, organofunctional silicones, or a silicone oil consisting of a cyclic concatenation of 4, 5, 6 or 7 D-siloxyl units of formula: (R) 2 SiO 2/2 formula wherein the symbols R, identical or different, represent each a linear or branched C 1 -C 6 alkyl radical, preferably methyl or an alkyl or arylalkyl radical having 6 to 8 carbon atoms, preferably phenyl. The invention also concerns an object incorporating or consisting of such a material.

Claims

exact text as granted — not AI-modified
1 - 12 . (canceled) 
   
   
       13 . A silicone material, optionally an adhesive material, for releasing an active molecule useful in cosmetics or in personal care or a pharmaceutically or biologically active molecule for pharmaceutical application, which is formed by an optionally adhesive, silicone material wherein there is incorporated said molecule and a compatibility agent which is miscible with the silicone components of the silicone material and wherein said active molecule is soluble, said compatibility agent being selected from the group consisting of isopropyl myristate, isopropyl palmitate, isononyl isononanoate, neopentyl glycol dioctanoate, branched paraffins, organofunctional silicones, and a silicone oil comprising a cyclic chain of 4, 5, 6 or 7 D siloxyl units of formula:
   (R) 2 SiO 2/2      wherein the symbols R, which are the same or different, each represent a linear or branched C 1 -C 6  alky radical, or an aryl or alkylaryl radical having 6 to 8 carbon atoms.   
   
   
       14 . The silicone material as defined by  claim 13 , wherein the compatibility agent content is from 5% to 50% by weight, expressed relative to the total composition. 
   
   
       15 . The silicone material as defined by  claim 13 , wherein the concentration of solubilized active material is at least 1.5 times greater than the maximum concentration which it would be possible to solubilize in the absence of the compatibility agent. 
   
   
       16 . The silicone material as defined by  claim 13 , wherein the amount of incorporated active molecule exceeds the solubilization capacity of the compatibility agent such that the active molecule is present in the solubilized and dispersed state. 
   
   
       17 . The silicone material as defined by  claim 13 , wherein the total content of active molecule and compatibility agent is up to 75% by weight of the total composition. 
   
   
       18 . The silicone material as defined by  claim 13 , wherein the concentration of active molecule solubilized in the silicone material is greater than or equal to 5, 10, 15, 20, 25 or 30% by weight based on the total weight of the material. 
   
   
       19 . The silicone material as defined by  claim 13 , wherein the total active molecule content is from 5% to 60% by weight based on the total weight of the material. 
   
   
       20 . The silicone material as defined by  claim 13 , wherein the silicone material is obtained by a hydrosilylation reaction between a polyorganosiloxane carrying alkenylsiloxy units and a polyorganosiloxane carrying hydrogenosiloxy units in the presence of a hydrosilylation catalyst. 
   
   
       21 . The silicone material as defined by  claim 13 , in gel or elastomer form. 
   
   
       22 . A shaped article comprising the silicone material as defined by  claim 13 . 
   
   
       23 . A shoe, a knee pad, a clothing, sports or bodily protection article, or any item to be worn by a living being, comprising the silicone material as defined by  claim 13 . 
   
   
       24 . The silicone material as defined by  claim 13 , wherein the active molecule is selected from the group consisting of methanol, methyl diisopropyl propionamide and mixtures thereof.

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