US2009130107A1PendingUtilityA1

Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders

Individually held — no corporate assignee on recordPriority: Dec 7, 1999Filed: Sep 24, 2008Published: May 21, 2009

Est. expiryDec 7, 2019(expired)· nominal 20-yr term from priority

Inventors:Austin Gurney Sudeepta Aggarwal Ming-Hong Xie Ellen M. Maruoka Jessica S. Foster Audrey Goddard William I. Wood

A61P 35/04C07K 14/54A61P 1/18G01N 2333/54G01N 33/6869

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Claims

Abstract

The present invention is directed to interleukin-22 polypeptides and nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

Claims

exact text as granted — not AI-modified

1 . A method for alleviating a pancreatic disorder in a mammal comprising administering to said mammal a therapeutically effective amount of an anti-IL-22 antibody. 
     
     
         2 . The method of  claim 1  wherein the mammal is a human. 
     
     
         3 . The method of  claim 2  wherein the pancreatic disorder is acute pancreatic, chronic pancreatic, pancreatic carcinoma, or pancreatic inflammation. 
     
     
         4 . The method of  claim 3  wherein the pancreatic carcinoma is acinar cell carcinoma or mixed cell population pancreatic cell carcinoma.

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