US2009131442A1PendingUtilityA1
Method of Treating Bone Pain Caused by Osteoarthritis
Est. expiryNov 16, 2027(~1.3 yrs left)· nominal 20-yr term from priority
Inventors:Joseph Bernstein
A61P 29/02A61K 31/519A61K 31/506A61K 31/53A61K 31/497A61K 31/4985A61P 19/08A61K 31/495A61P 19/02A61P 19/00
50
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Claims
Abstract
A method of treating bone pain caused by osteoarthritis by administering to a patient an effective amount of a composition containing a bone edema medication, such as a vasoactive medication or phosphodiesterase inhibitor, including a PDE-5 inhibitor.
Claims
exact text as granted — not AI-modified1 . A method of treating pain comprising administering to a patient a therapeutically effective amount of a pharmaceutically acceptable bone edema medication.
2 . The method of claim 1 , wherein the pain is caused by joint disease.
3 . The method of claim 2 , wherein the joint disease is osteoarthritis.
4 . The method of claim 1 , wherein the pharmaceutically acceptable bone edema medication is a vasoactive medication.
5 . The method of claim 1 , wherein the pharmaceutically acceptable bone edema medication is a phosphodiesterase inhibitor.
6 . The method of claim 5 , wherein the phosphodiesterase inhibitor is a subtype 5 phosphodiesterase enzyme (PDE5) selective inhibitor.
7 . The method of claim 6 , wherein the PDE5 selective inhibitor is selected from the group consisting of avanafil, sildenafil, tadalafil, udenafil, vardenafil and zaprinast.
8 . The method of claim 1 , wherein the step of administering is via an intramuscular route.
9 . The method of claim 1 , wherein the step of administering is via an oral route.
10 . The method of claim 1 , wherein the step of administering is via an intravenous route.
11 . The method of claim 1 , wherein the patient is a human.
12 . The method of claim 1 , wherein the patient is a non-human mammal.
13 . The method of claim 1 , wherein the therapeutically effective amount is a dose normally administered for known uses of the bone edema medication.
14 . The method of claim 1 , wherein 50 mg or less of the bone edema medication is administered.
15 . A method of reducing intraosseous hypertension comprising administering to a patient a therapeutically effective amount of a pharmaceutically acceptable bone edema medication.Join the waitlist — get patent alerts
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