Uses of antileukoprotease in carcinoma

Abstract

The present invention provides a method of detecting/monitoring tumor growth and progression in a tissue by measuring the level of antileukoprotease. Also provided is a method of treating an individual having a tumor by administering antileukoprotease to inhibit the activity of stratum corneum chymotryptic enzyme. Specifically, the tumor is an ovarian carcinoma.

1 . A method of treating an individual having a tumor selected from the group consisting of an ovarian tumor and ovarian-derived metastatic tumors, comprising:
 administering antileukoprotease to said individual.   
     
     
         2 . The method of  claim 1 , wherein said tumor is a low malignant potential tumor or an ovarian carcinoma. 
     
     
         3 . The method of  claim 2 , wherein said ovarian carcinoma is a serous carcinoma, a mucinous carcinoma, an endometrioid carcinoma, or a clear cell carcinomas. 
     
     
         4 . The method of  claim 1 , wherein said antileukoprotease is administered systemically. 
     
     
         5 . The method of  claim 1 , wherein said antileukoprotease is administered locally 
     
     
         6 . A method of preventing metastasis of a tumor selected from the group consisting of an ovarian tumor and ovarian derived metastatic tumors, comprising:
 administering antileukoprotease to an individual having said tumor.   
     
     
         7 . The method of  claim 6 , wherein said tumor is a low malignant potential tumor or an ovarian carcinoma. 
     
     
         8 . The method of  claim 7 , wherein said ovarian carcinoma is a serous carcinoma, a mucinous carcinoma, an endometrioid carcinoma, or a clear cell carcinoma. 
     
     
         9 . The method of  claim 6 , wherein said antileukoprotease is administered systemically. 
     
     
         10 . The method of  claim 6 , wherein said antileukoprotease is administered locally