US2009163495A1PendingUtilityA1

Morpholin-acetamide derivatives for the treatment of inflammatory diseases

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Assignee: GLAXO GROUP LTDPriority: Sep 29, 2000Filed: Feb 24, 2009Published: Jun 25, 2009
Est. expirySep 29, 2020(expired)· nominal 20-yr term from priority
A61P 37/02A61P 37/08A61P 9/10A61P 43/00A61P 31/18A61P 33/00A61P 3/10A61P 37/06A61P 33/12A61P 33/10A61P 9/14A61P 33/02A61P 25/28A61P 27/02A61P 25/00A61P 29/00A61P 17/06C07D 417/12A61P 11/06A61P 17/00C07D 413/14A61P 11/02C07D 413/12C07D 265/30A61P 17/04C07D 417/14A61P 19/02A61P 1/04
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Claims

Abstract

There are provided according to the invention, novel compounds of formula (I) wherein R 1 , R 2 , R 3 , R 4 , R 5 , X, a, b and Z are as defined in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.

Claims

exact text as granted — not AI-modified
1 . A compound which is N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-2-(5-methoxy-2-methyl-1H-indol-3-yl)acetamide or a salt thereof. 
     
     
         2 . The compound of  claim 1 , in which the salt is a physiologically acceptable salt. 
     
     
         3 . A pharmaceutical composition comprising: a compound of  claim 2  and one or more physiologically acceptable diluents or excipients. 
     
     
         4 . A method for the treatment of an inflammatory condition of the lung comprising administering to a patient an effective amount of a compound of  claim 1  or a pharmaceutically acceptable salt thereof. 
     
     
         5 . The method of  claim 4 , wherein the inflammatory condition of the lung is asthma.

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