US2009181043A1PendingUtilityA1
Method for Producing Human Anti-Thymocyte Immunoglobulins
Est. expirySep 28, 2020(expired)· nominal 20-yr term from priority
C07K 16/00A61P 43/00A61K 2039/505A61P 37/06C07K 16/18
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Abstract
Methods for producing improved anti-human thymocyte immunoglobulins from specific-pathogen-free animals are provided, without the need for an adsorption step on human tissues and the consequent drawbacks of such a step.
Claims
exact text as granted — not AI-modified1 - 10 . (canceled)
11 . A method for producing a therapeutic preparation of anti-human thymocyte immunoglobulins for use in human therapy, comprising the steps of:
a. injecting a cellular preparation of human thymocytes obtained from human thymus into a specific-pathogen-free (SPF) animal; b. collecting the immune serum produced by the animal; and c. isolating the anti-human thymocyte immunoglobulins from the collected immune serum; wherein said method includes no step of adsorption on human biological material in order to produce said therapeutic preparation of anti-human thymocyte immunoglobulins, and wherein the cellular preparation of human thymocytes obtained from human thymus used in step (a) consists of cells of lines in culture.
12 - 14 . (canceled)Join the waitlist — get patent alerts
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