Aligned particle based sensor elements

Abstract

The present invention relates to a sensor array for detecting an analyte in a fluid, comprising first and second sensors formed by chemically sensitive resistors, wherein the first sensor comprises a region of aligned conductive material; or where each of the sensors comprises alternating regions of nonconductive regions and aligned conductive regions with each resistor providing an electrical path through both the nonconductive region and the aligned conductive region, while each sensor manifests a different electrical resistance during contact with sample fluids having different analyte concentrations via the monitoring arrangement of having the sensors electrically connected to an electrical measuring apparatus. The aligned conductive particle material is aligned by exposure to either of an electric, magnetic, optical, photo-electric, electromagnetic or mechanical field, which serves to improve signal to noise ratio of vapor sensors allowing Lower Detection Limits for vapors being sensed. Such Lower Detection Limits allow for identification of lower concentrations of hazardous material and is advantageous in medical applications, such as detection of disease states in a patient.

1 . A system for detecting an analyte in a fluid, said system comprising:
 a sensor array comprising first and second sensors wherein said first sensor comprises a region of aligned conductive material which provides a response in the presence of said analyte;   an electrical measuring device electrically connected to the sensor array;   and a computer comprising a resident algorithm; the electrical measuring device detecting the response and the computer assembling the response into a sensor array response profile.   
   
   
       2 . The system for detecting an analyte in a fluid in accordance with  claim 1 , wherein said first and said second sensors are first and second chemically sensitive resistors, each chemically sensitive resistor comprising a plurality of alternating regions comprising a nonconductive region and an aligned conductive region that is compositionally different than said nonconductive region wherein,
 each resistor provides an electrical path through said nonconductive region and said aligned conductive region, a first electrical resistance when contacted with a first fluid comprising an analyte at a first concentration and a second different electrical resistance when contacted with a second fluid comprising said analyte at a second different concentration wherein,   the difference between said first electrical resistance and said second electrical resistance of said first chemically sensitive resistor being different from the difference between said first electrical resistance and said second electrical resistance of said second chemically sensitive resistor under the same conditions; and   the electrical measuring device detecting the first and said second electrical resistances in each of said chemically sensitive resistors and the computer assembling the resistances into a sensor array response profile.   
   
   
       3 . The system for detecting an analyte in a fluid in accordance with  claim 1 , wherein said conductive region is aligned by exposure to a member selected from the group consisting of an electric field, a thermal field, a magnetic field, an electromagnetic field, a photoelectric field, a light field or combinations thereof. 
   
   
       4 . The system for detecting an analyte in a fluid in accordance with  claim 3 , wherein said conductive region is electrically aligned. 
   
   
       5 . The system for detecting an analyte in a fluid in accordance with  claim 3 , wherein said conductive region is magnetically aligned. 
   
   
       6 . The system array for detecting an analyte in a fluid in accordance with  claim 3 , wherein said conductive region is photolytically aligned. 
   
   
       7 . A method for detecting the presence of an analyte in a fluid, said method comprising:
 providing a sensor array comprising first and second sensors, wherein said first sensor comprises a region of aligned conductive material; and   contacting said sensor array with said analyte to produce a response thereby detecting the presence of the analyte.   
   
   
       8 . The method for detecting an analyte in a fluid in accordance with  claim 7 , wherein said first and said second sensors are first and second chemically sensitive resistors each comprising a plurality of alternating regions comprising a nonconductive region, and an aligned conductive region that is compositionally different than the nonconductive material, and wherein each resistor provides an electrical path through said nonconducting regions and aligned conductive regions, a first electrical resistance when contacted with a first fluid comprising an analyte at a first concentration and a second different electrical resistance when contacted with a second fluid comprising said analyte at a second different concentration. 
   
   
       9 . The method for detecting an analyte in a fluid in accordance with  claim 7 , wherein said conductive region is electrically aligned. 
   
   
       10 . The method for detecting an analyte in a fluid in accordance with  claim 7 , wherein said conductive region is magnetically aligned. 
   
   
       11 . The method for detecting an analyte in a fluid in accordance with  claim 7 , wherein said conductive region is photolytically or mechanically aligned.