US2009203575A1PendingUtilityA1
Targeted therapeutic proteins
Est. expiryApr 30, 2021(expired)· nominal 20-yr term from priority
C07K 2319/50C07K 2319/06C12Y 302/01022C07K 2319/02A61K 38/44C07K 2319/00C07K 14/65A61K 47/6425A61K 47/64C07K 2319/74C07K 2319/21C07K 2317/77C12N 15/62C07K 2319/61A61K 47/642A61K 38/47C12N 9/0051C07K 2319/75C07K 16/28C12N 9/2402A61K 48/00A61P 3/00C07K 2319/01A61K 38/30C07K 2319/33A61K 35/54A61K 2039/515A61K 47/551A61K 39/3955A61K 35/12A61K 2039/505
71
PatentIndex Score
0
Cited by
0
References
0
Claims
Abstract
Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
Claims
exact text as granted — not AI-modified1 . A targeted therapeutic comprising:
a therapeutic agent that is therapeutically active in a mammalian lysosome; and
means for binding an extracellular domain of human cation-independent mannose-6-phosphate receptor in a mannose-6-phosphate-independent manner.
2 - 57 . (canceled)Cited by (0)
No later patents cite this yet.
References (0)
No backward citations on record.