US2009233959A1PendingUtilityA1

Beloxepin and analogs for the treatment of pain

76
Assignee: ADOLOR CORPPriority: Feb 19, 2008Filed: Feb 19, 2009Published: Sep 17, 2009
Est. expiryFeb 19, 2028(~1.6 yrs left)· nominal 20-yr term from priority
Inventors:Bertrand Le BourdonnecRoland E. Dolle
A61K 31/4353A61P 29/00A61P 25/00
76
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Claims

Abstract

This present disclosure provides methods of treating pain with beloxepin and/or beloxepin analogs.

Claims

exact text as granted — not AI-modified
1 . A method of treating pain in a mammal, comprising administering to a mammal suffering from pain an amount of beloxepin, or a salt thereof, effective to treat the pain. 
   
   
       2 . The method of  claim 1  in which the beloxepin is administered parenterally. 
   
   
       3 . The method of  claim 1  in which the beloxepin is administered orally. 
   
   
       4 . The method of  claim 1  in which the pain is acute or chronic pain of nociceptive origin. 
   
   
       5 . The method of  claim 4  in which the pain is inflammatory pain. 
   
   
       6 . The method of  claim 4  in which the pain is cancer pain. 
   
   
       7 . The method of  claim 1  in which the pain is chronic pain of non-nociceptive origin. 
   
   
       8 . The method of  claim 7  in which the pain is neuropathic pain. 
   
   
       9 . The method of  claim 1  in which the pain is visceral pain. 
   
   
       10 . The method of any one of  claims 1 - 9  in which the mammal is a human. 
   
   
       11 . A method of treating pain in a mammal, comprising administering to a mammal suffering from pain an amount of beloxepin and/or a beloxepin analog, or a salt thereof, effective to treat the pain. 
   
   
       12 . The method of  claim 11  in which the pain is acute or chronic pain of nociceptive origin. 
   
   
       13 . The method of  claim 12  in which the pain is inflammatory pain. 
   
   
       14 . The method of  claim 12  in which the pain is cancer pain. 
   
   
       15 . The method of  claim 11  in which the pain is chronic pain of non-nociceptive origin. 
   
   
       16 . The method of  claim 15  in which the pain is neuropathic pain. 
   
   
       17 . The method of  claim 11  in which the pain is visceral pain. 
   
   
       18 . The method of any one of  claims 11 - 17  in which the beloxepin, beloxepin analog and/or a salt thereof, is administered to the mammal in the form of a composition. 
   
   
       19 . The method of  claim 18  in which the beloxepin and/or beloxepin analog is included in the composition as a salt. 
   
   
       20 . The method of  claim 18  in which the mammal is a human. 
   
   
       21 . The method of  claim 18  in which the composition is formulated for oral administration 
   
   
       22 . The method of  claim 21  in which the mammal is a human.

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