US2009258948A1PendingUtilityA1

Pharmaceutical salts

Assignee: GRUENENTHAL CHEMIEPriority: Feb 28, 2001Filed: Jun 19, 2009Published: Oct 15, 2009
Est. expiryFeb 28, 2021(expired)· nominal 20-yr term from priority
A61P 25/00A61P 29/00A61K 9/0056A61P 13/00C07D 489/04C07C 215/64C07C 217/68C07B 2200/07A61K 9/0095C07D 275/06A61K 9/0058C07C 2601/14C07D 291/06C07C 215/62C07C 217/74C07C 215/54
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Claims

Abstract

The invention relates to pharmaceutical salts comprised of a pharmaceutical active substance and of at least one sugar substitute, to medicaments containing these salts, and to the use of these salts for producing medicaments.

Claims

exact text as granted — not AI-modified
1 .- 39 . (canceled) 
   
   
       40 . A pharmaceutical salt of a salt-forming pharmaceutical active compound and at least one salt-forming sugar substitute, wherein the salt-forming pharmaceutical active compound is a salt-forming 1-phenyl-3-dimethylaminopropane compound selected from the group consisting of: (a) (−)-(1R,2R)-3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)-phenol; (b) (1RS,3RS,6RS)-6-Dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol; and (c) (−)-(1R,2R)-3-(2-Dimethylaminomethyl-cyclohexyl)-phenol. 
   
   
       41 . The pharmaceutical salt according to  claim 40 , wherein the salt-forming pharmaceutical active compound is (−)-(1R,2R)-3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)-phenol. 
   
   
       42 . The pharmaceutical salt according to  claim 40 , wherein the salt-forming pharmaceutical active compound is (1RS,3RS,6RS)-6-Dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol. 
   
   
       43 . The pharmaceutical salt according to  claim 40 , wherein the salt-forming pharmaceutical active compound is (−)-(1R,2R)-3-(2-Dimethylaminomethyl-cyclohexyl)-phenol. 
   
   
       44 . A pharmaceutical composition comprising a therapeutically effective amount of the pharmaceutical salt according to  claim 40  and optionally one or more physiologically tolerable excipients. 
   
   
       45 . A method of controlling pain comprising administering to a patient in need thereof a pain-controlling effective amount of the pharmaceutical salt of  claim 40 . 
   
   
       46 . A method of controlling urinary incontinence comprising administering to a patient in need thereof an urinary incontinence-controlling effective amount of the pharmaceutical salt of  claim 40 .

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